CTNNB1 anticorps

N° du produit ABIN7266138

Détail du produit anti-CTNNB1 anticorps

Antigène: CTNNB1 (Catenin (Cadherin-Associated Protein), beta 1, 88kDa (CTNNB1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp CTNNB1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP)

Fonction: [KO Validated] β-Catenin Rabbit mAb

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Monoclonal Antibodies

Purification: Affinity purification

Classe de qualité: KO Validated

Immunogène: A synthesized peptide derived from human beta Catenin.

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200,IP,1:50 - 1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur CTNNB1

Antigène: CTNNB1 (Catenin (Cadherin-Associated Protein), beta 1, 88kDa (CTNNB1))

Autre désignation: CTNNB1 (CTNNB1 Produits)

Synonymes: anticorps Jup, anticorps LOC100217813, anticorps CTNNB1, anticorps CTNNB, anticorps Bfc, anticorps Catnb, anticorps Mesc, anticorps ctnnb, anticorps id:ibd2058, anticorps wu:fb73e10, anticorps wu:fi81c06, anticorps wu:fk25h01, anticorps ctnnb1, anticorps CHBCAT, anticorps MRD19, anticorps armadillo, anticorps beta-catenin, anticorps catenin beta 1, anticorps catenin (cadherin associated protein), beta 1, anticorps catenin (cadherin-associated protein), beta 1, anticorps catenin beta 1 S homeolog, anticorps catenin beta 1 L homeolog, anticorps CTNNB1, anticorps Ctnnb1, anticorps ctnnb1, anticorps ctnnb1.S, anticorps ctnnb1.L

Sujet: The protein encoded by this gene is part of a complex of proteins that constitute adherens junctions (AJs). AJs are necessary for the creation and maintenance of epithelial cell layers by regulating cell growth and adhesion between cells. The encoded protein also anchors the actin cytoskeleton and may be responsible for transmitting the contact inhibition signal that causes cells to stop dividing once the epithelial sheet is complete. Finally, this protein binds to the product of the APC gene, which is mutated in adenomatous polyposis of the colon. Mutations in this gene are a cause of colorectal cancer (CRC), pilomatrixoma (PTR), medulloblastoma (MDB), and ovarian cancer. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2016],CTNNB,MRD19,armadillo,beta Catenin,CTNNB1,Angiogenesis,Apoptosis,Cancer,Cardiovascular,Cell Adhesion,Cell Adhesion_Cadherins,Cell Adhesion_Tight Junctions,Cell Biology & Developmental Biology,Cytoskeleton,Cytoskeleton_Microfilaments,Epigenetics & Nuclear Signaling,ErbB-HER Signaling Pathway,ESC Pluripotency and Differentiation,Immunology & Inflammation,Invasion and Metastasis,Neuroscience,Protein phosphorylation,Signal Transduction,Stem Cells,Transcription Factors,Wnt/β-Catenin Signaling Pathway,CTNNB1

Poids moléculaire: 92kDa

ID gène: 1499

UniProt: P35222

Pathways: Signalisation WNT, Intracellular Steroid Hormone Receptor Signaling Pathway, Peptide Hormone Metabolism, Regulation of Muscle Cell Differentiation, Cell-Cell Junction Organization, Tube Formation, Maintenance of Protein Location, Signaling Events mediated by VEGFR1 and VEGFR2