C6orf150 anticorps (pSer420)

N° du produit ABIN7266387

Détail du produit anti-C6orf150 anticorps

Antigène: C6orf150 (Chromosome 6 Open Reading Frame 150 (C6orf150))

Épitope: pSer420

Reactivité: Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp C6orf150 est non-conjugé

Application: Western Blotting (WB)

Fonction: Phospho-CGAS-S420 Rabbit pAb

Réactivité croisée: Humain, Rat

Attributs du produit: Phosphorylated Antibodies

Purification: Affinity purification

Immunogène: A phospho synthetic peptide corresponding to residues surrounding S420 of Mouse CGAS.

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur C6orf150

Antigène: C6orf150 (Chromosome 6 Open Reading Frame 150 (C6orf150))

Autre désignation: CGAS (C6orf150 Produits)

Synonymes: anticorps C6orf150, anticorps cGAS, anticorps h-cGAS, anticorps Mab-21 domain containing 1, anticorps cyclic GMP-AMP synthase, anticorps MB21D1, anticorps CGAS

Sujet: The protein encoded by this gene is a DNA binding cytosolic protein that catalyzes the synthesis of cyclic guanosine monophosphate-adenosine monophosphate (cGAMP) after sensing the presence of DNA in the cytoplasm. cGAMP binds another protein, Stimulator of interferon genes (STING), leading to the induction of interferons, and a host immune response. Reduced expression of this gene inhibits interferon induction in the presence of some viral infections. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014],E330016A19Rik, cGAS,CGAS

ID gène: 214763

UniProt: Q8C6L5

Pathways: Activation of Innate immune Response