C4A anticorps (AA 1200-1446)

N° du produit ABIN7266482

Détail du produit anti-C4A anticorps

Antigène: C4A (C4a) (Complement Fragment C4a (C4a))

Épitope: AA 1200-1446

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp C4A est non-conjugé

Application: Western Blotting (WB)

Fonction: Complement C4A Rabbit pAb

Séquence: LTLTKAPVDL LGVAHNNLMA MAQETGDNLY WGSVTGSQSN AVSPTPAPRN PSDPMPQAPA LWIETTAYAL LHLLLHEGKA EMADQASAWL TRQGSFQGGF RSTQDTVIAL DALSAYWIAS HTTEERGLNV TLSSTGRNGF KSHALQLNNR QIRGLEEELQ FSLGSKINVK VGGNSKGTLK VLRTYNVLDM KNTTCQDLQI EVTVKGHVEY TMEANEDYED YEYDELPAKD DPDAPLQPVT PLQLFEG

Réactivité croisée: Humain

Attributs du produit: Polyclonal Antibodies

Purification: Affinity purification

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 1200-1446 of human Complement C4A (NP_009224.2).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur C4A

Antigène: C4A (C4a) (Complement Fragment C4a (C4a))

Autre désignation: C4A (C4a Produits)

Synonymes: anticorps C4, anticorps C4A2, anticorps C4A3, anticorps C4A4, anticorps C4A6, anticorps C4AD, anticorps C4S, anticorps CO4, anticorps CPAMD2, anticorps RG, anticorps Slp, anticorps C4-1, anticorps C4b, anticorps complement C4A (Rodgers blood group), anticorps complement component 4A (Rodgers blood group), anticorps C4A, anticorps C4a

Sujet: This gene encodes the acidic form of complement factor 4, part of the classical activation pathway. The protein is expressed as a single chain precursor which is proteolytically cleaved into a trimer of alpha, beta, and gamma chains prior to secretion. The trimer provides a surface for interaction between the antigen-antibody complex and other complement components. The alpha chain is cleaved to release C4 anaphylatoxin, an antimicrobial peptide and a mediator of local inflammation. Deficiency of this protein is associated with systemic lupus erythematosus and type I diabetes mellitus. This gene localizes to the major histocompatibility complex (MHC) class III region on chromosome 6. Varying haplotypes of this gene cluster exist, such that individuals may have 1, 2, or 3 copies of this gene. Two transcript variants encoding different isoforms have been found for this gene.,C4A,C4,C4A2,C4A3,C4A4,C4A6,C4AD,C4S,CO4,CPAMD2,RG,Immunology & Inflammation,Cell Intrinsic Innate Immunity Signaling Pathway,C4A

Poids moléculaire: 187kDa/192kDa

ID gène: 720

UniProt: P0C0L4

Pathways: Système du Complément