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CRTC1 anticorps (AA 1-200)

CRTC1 Reactivité: Humain WB Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN7266518
  • Antigène Voir toutes CRTC1 Anticorps
    CRTC1 (CREB Regulated Transcription Coactivator 1 (CRTC1))
    Épitope
    • 22
    • 5
    • 5
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    AA 1-200
    Reactivité
    • 67
    • 37
    • 25
    • 15
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 55
    • 13
    • 1
    Lapin
    Clonalité
    • 55
    • 14
    Polyclonal
    Conjugué
    • 32
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp CRTC1 est non-conjugé
    Application
    • 52
    • 25
    • 20
    • 13
    • 9
    • 8
    • 8
    • 7
    • 6
    • 6
    • 3
    • 1
    • 1
    Western Blotting (WB)
    Fonction
    CRTC1 Rabbit pAb
    Séquence
    MATSNNPRKF SEKIALHNQK QAEETAAFEE VMKDLSLTRA ARLQLQKSQY LQLGPSRGQY YGGSLPNVNQ IGSGTMDLPF QTPFQSSGLD TSRTTRHHGL VDRVYRERGR LGSPHRRPLS VDKHGRQADS CPYGTMYLSP PADTSWRRTN SDSALHQSTM TPTQPESFSS GSQDVHQKRV LLLTVPGMEE TTSEADKNLS
     Réactivité croisée
    Souris, Rat
    Attributs du produit
    Polyclonal Antibodies
    Purification
    Affinity purification
    Immunogène
    Recombinant fusion protein containing a sequence corresponding to amino acids 1-200 of human CRTC1 (NP_056136.2).
    Isotype
    IgG
    Top Product
    Discover our top product CRTC1 Anticorps primaire
  • Indications d'application
    WB,1:200 - 1:2000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C. Avoid freeze / thaw cycles.
  • Antigène
    CRTC1 (CREB Regulated Transcription Coactivator 1 (CRTC1))
    Autre désignation
    CRTC1 (CRTC1 Produits)
    Synonymes
    anticorps MECT1, anticorps TORC-1, anticorps TORC1, anticorps WAMTP1, anticorps AI413414, anticorps Mect1, anticorps R74955, anticorps mKIAA0616, anticorps CRTC1, anticorps crtc1, anticorps fc68c05, anticorps pde4cb, anticorps si:ch211-255d18.1, anticorps si:ch211-255d18.8, anticorps wu:fc68c05, anticorps CREB regulated transcription coactivator 1, anticorps CREB regulated transcription coactivator 1b, anticorps CRTC1, anticorps Crtc1, anticorps crtc1, anticorps crtc1b
    Sujet
    Transcriptional coactivator for CREB1 which activates transcription through both consensus and variant cAMP response element (CRE sites. Acts as a coactivator, in the SIK/TORC signaling pathway, being active when dephosphorylated and acts independently of CREB1 'Ser-133' phosphorylation. Enhances the interaction of CREB1 with TAF4. Regulates the expression of specific CREB-activated genes such as the steroidogenic gene, StAR. Potent coactivator of PGC1alpha and inducer of mitochondrial biogenesis in muscle cells. In the hippocampus, involved in late-phase long-term potentiation (L-LTP maintenance at the Schaffer collateral-CA1 synapses. May be required for dendritic growth of developing cortical neurons (By similarity. In concert with SIK1, regulates the light-induced entrainment of the circadian clock. In response to light stimulus, coactivates the CREB-mediated transcription of PER1 which plays an important role in the photic entrainment of the circadian clock.,CRTC1,MECT1,TORC-1,TORC1,WAMTP1,Epigenetics & Nuclear Signaling,Signal Transduction,Endocrine & Metabolism,Mitochondrial metabolism,Mitochondrial Biogenesis,CRTC1
    Poids moléculaire
    62kDa/67kDa/68kDa
    ID gène
    23373
    UniProt
    Q6UUV9
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