CAND1 anticorps (AA 750-980)
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- Antigène Voir toutes CAND1 Anticorps
- CAND1 (Cullin-Associated and Neddylation-Dissociated 1 (CAND1))
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Épitope
- AA 750-980
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp CAND1 est non-conjugé
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Application
- Western Blotting (WB), Immunohistochemistry (IHC)
- Fonction
- CAND1 Rabbit pAb
- Séquence
- GALSAMLDFF QALVVTGTNN LGYMDLLRML TGPVYSQSTA LTHKQSYYSI AKCVAALTRA CPKEGPAVVG QFIQDVKNSR STDSIRLLAL LSLGEVGHHI DLSGQLELKS VILEAFSSPS EEVKSAASYA LGSISVGNLP EYLPFVLQEI TSQPKRQYLL LHSLKEIISS ASVVGLKPYV ENIWALLLKH CECAEEGTRN VVAECLGKLT LIDPETLLPR LKGYLISGSS Y
- Réactivité croisée
- Humain, Souris, Rat
- Attributs du produit
- Polyclonal Antibodies
- Purification
- Affinity purification
- Immunogène
- Recombinant fusion protein containing a sequence corresponding to amino acids 750-980 of human CAND1 (NP_060918.2).
- Isotype
- IgG
- Top Product
- Discover our top product CAND1 Anticorps primaire
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- Indications d'application
- WB,1:500 - 1:2000,IHC,1:50 - 1:100
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20°C. Avoid freeze / thaw cycles.
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- Antigène
- CAND1 (Cullin-Associated and Neddylation-Dissociated 1 (CAND1))
- Autre désignation
- CAND1 (CAND1 Produits)
- Sujet
- This gene encodes an essential regulator of Cullin-RING ubiquitin ligases, which are in involved in ubiquitinylation of proteins degraded by the Ub proteasome system. The encoded protein binds to unneddylated cullin-RING box protein complexes and acts as an inhibitor of cullin neddylation and of Skp1, cullin, and F box ubiquitin ligase complex assembly and activity. In mammalian cell culture, this protein predominantly localizes to the cytoplasm. Knockdown of this gene in preadipocytes results in blocked adipogenesis. Alternative splicing results in multiple transcript variants.,CAND1,TIP120,TIP120A,Epigenetics & Nuclear Signaling,Cell Biology & Developmental Biology,Cell Cycle,Ubiquitin,CAND1
- Poids moléculaire
- 45kDa/117kDa/136kDa
- ID gène
- 55832
- UniProt
- Q86VP6
- Pathways
- Regulation of Actin Filament Polymerization
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