DMP1 anticorps (AA 561-760)
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- Antigène Voir toutes DMP1 (DMTF1) Anticorps
- DMP1 (DMTF1) (Cyclin D Binding Myb-Like Transcription Factor 1 (DMTF1))
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Épitope
- AA 561-760
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp DMP1 est non-conjugé
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Application
- Western Blotting (WB)
- Fonction
- DMTF1 Rabbit pAb
- Séquence
- VTVQCHTPRV IIQTVATEDI TSSISQAELT VDSDIQSSDF PEPPDALEAD TFPDEIHHPK MTVEPSFNDA HVSKFSDQNS TELMNSVMVR TEEEISDTDL KQEESPSDLA SAYVTEGLES PTIEEQVDQT IDDETILIVP SPHGFIQASD VIDTESVLPL TTLTDPILQH HQEESNIIGS SLGSPVSEDS KDVEDLVNCH
- Réactivité croisée
- Humain
- Attributs du produit
- Polyclonal Antibodies
- Purification
- Affinity purification
- Immunogène
- Recombinant fusion protein containing a sequence corresponding to amino acids 561-760 of human DMTF1 (NP_066968.3).
- Isotype
- IgG
- Top Product
- Discover our top product DMTF1 Anticorps primaire
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- Indications d'application
- WB,1:500 - 1:2000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20°C. Avoid freeze / thaw cycles.
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- Antigène
- DMP1 (DMTF1) (Cyclin D Binding Myb-Like Transcription Factor 1 (DMTF1))
- Autre désignation
- DMTF1 (DMTF1 Produits)
- Synonymes
- anticorps DMP1, anticorps DMTF, anticorps hDMP1, anticorps Dimp, anticorps Dmp1, anticorps DMTF1, anticorps zgc:92448, anticorps cyclin D binding myb like transcription factor 1, anticorps cyclin D binding myb-like transcription factor 1, anticorps DMTF1, anticorps Dmtf1, anticorps dmtf1
- Sujet
- This gene encodes a transcription factor that contains a cyclin D-binding domain, three central Myb-like repeats, and two flanking acidic transactivation domains at the N- and C-termini. The encoded protein is induced by the oncogenic Ras signaling pathway and functions as a tumor suppressor by activating the transcription of ARF and thus the ARF-p53 pathway to arrest cell growth or induce apoptosis. It also activates the transcription of aminopeptidase N and may play a role in hematopoietic cell differentiation. The transcriptional activity of this protein is regulated by binding of D-cyclins. This gene is hemizygously deleted in approximately 40 % of human non-small-cell lung cancer and is a potential prognostic and gene-therapy target for non-small-cell lung cancer. Multiple transcript variants encoding different isoforms have been found for this gene.,DMTF1,DMP1,DMTF,MRUL,hDMP1,Epigenetics & Nuclear Signaling,Transcription Factors,Cancer,Tumor suppressors,p53 pathway,Cell Biology & Developmental Biology,Cell Cycle,Cell cycle inhibitors,Cyclins,DMTF1
- ID gène
- 9988
- UniProt
- Q9Y222
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