DNER anticorps (AA 140-240)
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- Antigène Voir toutes DNER Anticorps
- DNER (delta/notch-Like EGF Repeat Containing (DNER))
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Épitope
- AA 140-240
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp DNER est non-conjugé
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Application
- Western Blotting (WB), Immunofluorescence (IF)
- Fonction
- DNER Rabbit pAb
- Séquence
- PATGWTESMA PRQLQPVPAT QEPDKILPRS QATVTLPTWQ PKTGQKVVEM KWDQVEVIPD IACGNASSNS SAGGRLVSFE VPQNTSVKIR QDATASLILL W
- Réactivité croisée
- Humain, Souris, Rat
- Attributs du produit
- Polyclonal Antibodies
- Purification
- Affinity purification
- Immunogène
- Recombinant fusion protein containing a sequence corresponding to amino acids 140-240 of human DNER (NP_620711.3).
- Isotype
- IgG
- Top Product
- Discover our top product DNER Anticorps primaire
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- Indications d'application
- WB,1:200 - 1:2000,IF,1:50 - 1:200
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20°C. Avoid freeze / thaw cycles.
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- Antigène
- DNER (delta/notch-Like EGF Repeat Containing (DNER))
- Autre désignation
- DNER (DNER Produits)
- Synonymes
- anticorps UNQ26, anticorps bet, anticorps A930026D19Rik, anticorps BET, anticorps Bret, anticorps delta/notch like EGF repeat containing, anticorps delta and Notch-like epidermal growth factor-related receptor, anticorps delta/notch-like EGF repeat containing, anticorps DNER, anticorps LOC540552, anticorps Dner
- Sujet
- DNER (Delta/Notch-like EGF-related receptor), also known as BET (brain-specific EGF-like transmembrane protein), is a type I transmembrane glycoprotein of the Notch/Delta family . In the mouse, DNER has been detected as 90, 120 and 150 kDa forms which are probably variably glycosylated .Activator of the NOTCH1 pathway. May mediate neuron-glia interaction during astrocytogenesis.DNER associates with protein tyrosine phosphatase zeta (PTP zeta ), which is the receptor of pleiotrophin (PTN). PTP zeta -PTN-DNER signaling has been implicated in the regulation of neuritogenesis. Expression of DNER in glioblastoma stem-like cells inhibits formation of neurospheres in vitro, while in vivo it induces differentiation and inhibits growth of xenografts, thus acting as a tumor suppressor.,DNER,UNQ26,bet,Neuroscience,Stem Cells,DNER
- Poids moléculaire
- 78kDa
- ID gène
- 92737
- UniProt
- Q8NFT8
- Pathways
- Skeletal Muscle Fiber Development
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