DVL1 anticorps (AA 510-640)

N° du produit ABIN7266796

Détail du produit anti-DVL1 anticorps

Antigène: DVL1 (Dishevelled Segment Polarity Protein 1 (DVL1))

Épitope: AA 510-640

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DVL1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Fonction: DVL1 Rabbit pAb

Séquence: GQGYPYQYPG PPPCFPPAYQ DPGFSYGSGS TGSQQSEGSK SSGSTRSSRR APGREKERRA AGAGGSGSES DHTAPSGVGS SWRERPAGQL SRGSSPRSQA SATAPGLPPP HPTTKAYTVV GGPPGGPPVR E

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Polyclonal Antibodies

Purification: Affinity purification

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 510-640 of human DVL1 (NP_004412.2).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000,IHC,1:50 - 1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur DVL1

Antigène: DVL1 (Dishevelled Segment Polarity Protein 1 (DVL1))

Autre désignation: DVL1 (DVL1 Produits)

Sujet: DVL1, the human homolog of the Drosophila dishevelled gene (dsh) encodes a cytoplasmic phosphoprotein that regulates cell proliferation, acting as a transducer molecule for developmental processes, including segmentation and neuroblast specification. DVL1 is a candidate gene for neuroblastomatous transformation. The Schwartz-Jampel syndrome and Charcot-Marie-Tooth disease type 2A have been mapped to the same region as DVL1. The phenotypes of these diseases may be consistent with defects which might be expected from aberrant expression of a DVL gene during development.,DVL1,DRS2,DVL,DVL1L1,DVL1P1,Epigenetics & Nuclear Signaling,Translation Control,Regulation of eIF4 and p70 S6 Kinase,Signal Transduction,mTOR Signaling Pathway,Cell Biology & Developmental Biology,Hippo Signaling Pathway,Wnt/β-Catenin Signaling Pathway,Stem Cells,DVL1

Poids moléculaire: 72kDa/75kDa

ID gène: 1855

UniProt: O14640

Pathways: Signalisation WNT, Synaptic Membrane, Skeletal Muscle Fiber Development