DCLK1 anticorps (AA 630-729)

N° du produit ABIN7266842

Détail du produit anti-DCLK1 anticorps

Antigène: DCLK1 (Doublecortin-Like Kinase 1 (DCLK1))

Épitope: AA 630-729

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DCLK1 est non-conjugé

Application: Western Blotting (WB)

Fonction: DCAMKL1/DCLK1 Rabbit pAb

Séquence: VDVDQRFSAV QVLEHPWVND DGLPENEHQL SVAGKIKKHF NTGPKPNSTA AGVSVIALDH GFTIKRSGSL DYYQQPGMYW IRPPLLIRRG RFSDEDATRM

Réactivité croisée: Humain, Souris

Attributs du produit: Polyclonal Antibodies

Purification: Affinity purification

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 630-729 of human DCAMKL1/DCAMKL1/DCLK1 (NP_004725.1).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur DCLK1

Antigène: DCLK1 (Doublecortin-Like Kinase 1 (DCLK1))

Autre désignation: DCLK1 (DCLK1 Produits)

Synonymes: anticorps DCLK1, anticorps DCAMKL1, anticorps dcamkl1, anticorps dclk1, anticorps wu:fc51f11, anticorps zgc:153709, anticorps MGC145348, anticorps CL1, anticorps CLICK1, anticorps DCDC3A, anticorps DCLK, anticorps 1700113D08Rik, anticorps 2810480F11Rik, anticorps AI836758, anticorps Click-I, anticorps Cpg16, anticorps Dcamkl1, anticorps Dcl, anticorps Dclk, anticorps mKIAA0369, anticorps Ania4, anticorps doublecortin like kinase 1, anticorps doublecortin-like kinase 1a, anticorps serine/threonine-protein kinase DCLK1, anticorps doublecortin-like kinase 2, anticorps doublecortin-like kinase 1, anticorps DCLK1, anticorps dclk1a, anticorps LOC587664, anticorps dclk2, anticorps LOC100539645, anticorps Dclk1

Sujet: This gene encodes a member of the protein kinase superfamily and the doublecortin family. The protein encoded by this gene contains two N-terminal doublecortin domains, which bind microtubules and regulate microtubule polymerization, a C-terminal serine/threonine protein kinase domain, which shows substantial homology to Ca2+/calmodulin-dependent protein kinase, and a serine/proline-rich domain in between the doublecortin and the protein kinase domains, which mediates multiple protein-protein interactions. The microtubule-polymerizing activity of the encoded protein is independent of its protein kinase activity. The encoded protein is involved in several different cellular processes, including neuronal migration, retrograde transport, neuronal apoptosis and neurogenesis. This gene is up-regulated by brain-derived neurotrophic factor and associated with memory and general cognitive abilities. Multiple transcript variants generated by two alternative promoter usage and alternative splicing have been reported, but the full-length nature and biological validity of some variants have not been defined. These variants encode different isoforms, which are differentially expressed and have different kinase activities.,DCLK1,CL1,CLICK1,DCAMKL1,DCDC3A,DCLK,Signal Transduction,Kinase,Neuroscience,DCLK1

Poids moléculaire: 46kDa/47kDa/81kDa/82kDa

ID gène: 9201

UniProt: O15075