DUSP8 anticorps

N° du produit ABIN7266849

Détail du produit anti-DUSP8 anticorps

Antigène: DUSP8 (Dual Specificity Phosphatase 8 (DUSP8))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DUSP8 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF)

Fonction: DUSP8 Rabbit pAb

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Polyclonal Antibodies

Purification: Affinity purification

Immunogène: Recombinant protein of human DUSP8

Isotype: IgG

Information d'application

Indications d'application: WB,1:200 - 1:1000,IF,1:50 - 1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur DUSP8

Antigène: DUSP8 (Dual Specificity Phosphatase 8 (DUSP8))

Autre désignation: DUSP8 (DUSP8 Produits)

Synonymes: anticorps zgc:77593, anticorps C11orf81, anticorps HB5, anticorps HVH-5, anticorps HVH8, anticorps 5530400B01Rik, anticorps AI593498, anticorps Nttp1, anticorps Hb5, anticorps M3/6, anticorps DUSP8, anticorps dual specificity phosphatase 8, anticorps dual specificity phosphatase 8a, anticorps dual specificity protein phosphatase 8, anticorps DUSP8, anticorps dusp8, anticorps dusp8a, anticorps DSP8, anticorps Dusp8, anticorps LOC615727

Sujet: The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which is associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene product inactivates SAPK/JNK and p38, is expressed predominantly in the adult brain, heart, and skeletal muscle, is localized in the cytoplasm, and is induced by nerve growth factor and insulin. An intronless pseudogene for DUSP8 is present on chromosome 10q11.2.,DUSP8,C11orf81,HB5,HVH-5,HVH8,Signal Transduction,DUSP8

Poids moléculaire: 65kDa

ID gène: 1850

UniProt: Q13202