GNE anticorps

N° du produit ABIN7267398

Détail du produit anti-GNE anticorps

Antigène: GNE (Glucosamine (UDP-N-Acetyl)-2-Epimerase/N-Acetylmannosamine Kinase (GNE))

Reactivité: Humain

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp GNE est non-conjugé

Application: Western Blotting (WB)

Fonction: GNE Rabbit mAb

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Monoclonal Antibodies

Purification: Affinity purification

Immunogène: Recombinant protein of Human GNE.

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur GNE

Antigène: GNE (Glucosamine (UDP-N-Acetyl)-2-Epimerase/N-Acetylmannosamine Kinase (GNE))

Autre désignation: GNE (GNE Produits)

Synonymes: anticorps DMRV, anticorps GLCNE, anticorps IBM2, anticorps UAE1, anticorps zgc:77657, anticorps GNE, anticorps MGC145505, anticorps NM, anticorps Uae1, anticorps 2310066H07Rik, anticorps glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase, anticorps GNE, anticorps gne, anticorps Gne

Sujet: The protein encoded by this gene is a bifunctional enzyme that initiates and regulates the biosynthesis of N-acetylneuraminic acid (NeuAc), a precursor of sialic acids. It is a rate-limiting enzyme in the sialic acid biosynthetic pathway. Sialic acid modification of cell surface molecules is crucial for their function in many biologic processes, including cell adhesion and signal transduction. Differential sialylation of cell surface molecules is also implicated in the tumorigenicity and metastatic behavior of malignant cells. Mutations in this gene are associated with sialuria, autosomal recessive inclusion body myopathy, and Nonaka myopathy. Alternative splicing of this gene results in transcript variants encoding different isoforms.,GNE,DMRV,GLCNE,IBM2,NM,Uae1,Signal Transduction,Kinase,Cell Biology & Developmental Biology,Cardiovascular,Blood,GNE

Poids moléculaire: 66kDa/71kDa/78kDa/79kDa/83kDa

ID gène: 10020

UniProt: Q9Y223