GSTA3 anticorps (AA 1-222)
Aperçu rapide pour GSTA3 anticorps (AA 1-222) (ABIN7267440)
Antigène
Voir toutes GSTA3 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 1-222
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Fonction
- GSTA3 Rabbit pAb
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Séquence
- MAGKPKLHYF NGRGRMEPIR WLLAAAGVEF EEKFIGSAED LGKLRNDGSL MFQQVPMVEI DGMKLVQTRA ILNYIASKYN LYGKDIKERA LIDMYTEGMA DLNEMILLLP LCRPEEKDAK IALIKEKTKS RYFPAFEKVL QSHGQDYLVG NKLSRADISL VELLYYVEEL DSSLISNFPL LKALKTRISN LPTVKKFLQP GSPRKPPADA KALEEARKIF RF
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Réactivité croisée
- Humain, Souris, Rat
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Attributs du produit
- Polyclonal Antibodies
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Purification
- Affinity purification
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Immunogène
- Recombinant fusion protein containing a sequence corresponding to amino acids 1-222 of human GSTA3 (NP_000838.3).
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Isotype
- IgG
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Indications d'application
- WB,1:500 - 1:2000,IF,1:50 - 1:100
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20°C. Avoid freeze / thaw cycles.
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- GSTA3 (Glutathione S-Transferase alpha 3 (GSTA3))
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Autre désignation
- GSTA3
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Sujet
- Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. These enzymes are involved in cellular defense against toxic, carcinogenic, and pharmacologically active electrophilic compounds. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. This gene encodes a glutathione S-tranferase belonging to the alpha class genes that are located in a cluster mapped to chromosome 6. Genes of the alpha class are highly related and encode enzymes with glutathione peroxidase activity. However, during evolution, this alpha class gene diverged accumulating mutations in the active site that resulted in differences in substrate specificity and catalytic activity. The enzyme encoded by this gene catalyzes the double bond isomerization of precursors for progesterone and testosterone during the biosynthesis of steroid hormones. An additional transcript variant has been identified, but its full length sequence has not been determined. [provided by RefSeq, Jul 2008],GSTA3,GSTA3-3,GTA3,Cancer,Signal Transduction,Cell Biology & Developmental Biology,Growth factor,Endocrine & Metabolism,Drug metabolism,GSTA3
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Poids moléculaire
- 25kDa
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ID gène
- 2940
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UniProt
- Q16772
Antigène
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