GSTA3 anticorps (AA 1-222)

N° du produit ABIN7267440

Détail du produit anti-GSTA3 anticorps

Antigène: GSTA3 (Glutathione S-Transferase alpha 3 (GSTA3))

Épitope: AA 1-222

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GSTA3 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF)

Fonction: GSTA3 Rabbit pAb

Séquence: MAGKPKLHYF NGRGRMEPIR WLLAAAGVEF EEKFIGSAED LGKLRNDGSL MFQQVPMVEI DGMKLVQTRA ILNYIASKYN LYGKDIKERA LIDMYTEGMA DLNEMILLLP LCRPEEKDAK IALIKEKTKS RYFPAFEKVL QSHGQDYLVG NKLSRADISL VELLYYVEEL DSSLISNFPL LKALKTRISN LPTVKKFLQP GSPRKPPADA KALEEARKIF RF

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Polyclonal Antibodies

Purification: Affinity purification

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 1-222 of human GSTA3 (NP_000838.3).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000,IF,1:50 - 1:100

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur GSTA3

Antigène: GSTA3 (Glutathione S-Transferase alpha 3 (GSTA3))

Autre désignation: GSTA3 (GSTA3 Produits)

Synonymes: anticorps GSTA3, anticorps GST, anticorps GSTA1, anticorps GSTA3-3, anticorps GTA3, anticorps GSTA2, anticorps Gst2-3, anticorps Yc2, anticorps glutathione S-transferase alpha 3, anticorps glutathione S-transferase A2, anticorps glutathione S-transferase, anticorps glutathione S-transferase, alpha 3, anticorps glutathione S-transferase Yc, anticorps GSTA3, anticorps LOC474938, anticorps gsta3, anticorps Gsta3, anticorps LOC100328911

Sujet: Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. These enzymes are involved in cellular defense against toxic, carcinogenic, and pharmacologically active electrophilic compounds. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. This gene encodes a glutathione S-tranferase belonging to the alpha class genes that are located in a cluster mapped to chromosome 6. Genes of the alpha class are highly related and encode enzymes with glutathione peroxidase activity. However, during evolution, this alpha class gene diverged accumulating mutations in the active site that resulted in differences in substrate specificity and catalytic activity. The enzyme encoded by this gene catalyzes the double bond isomerization of precursors for progesterone and testosterone during the biosynthesis of steroid hormones. An additional transcript variant has been identified, but its full length sequence has not been determined. [provided by RefSeq, Jul 2008],GSTA3,GSTA3-3,GTA3,Cancer,Signal Transduction,Cell Biology & Developmental Biology,Growth factor,Endocrine & Metabolism,Drug metabolism,GSTA3

Poids moléculaire: 25kDa

ID gène: 2940

UniProt: Q16772