Granulin anticorps

N° du produit ABIN7267505

Détail du produit anti-Granulin anticorps

Antigène: Granulin (GRN)

Reactivité: Humain

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp Granulin est non-conjugé

Application: Western Blotting (WB)

Fonction: Granulin Rabbit mAb

Réactivité croisée: Humain

Attributs du produit: Monoclonal Antibodies

Purification: Affinity purification

Immunogène: A synthesized peptide derived from human Granulin

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur Granulin

Antigène: Granulin (GRN)

Autre désignation: GRN (GRN Produits)

Synonymes: anticorps GRN, anticorps grn, anticorps wu:fb11g12, anticorps wu:fj18f05, anticorps MGC53354, anticorps DKFZp459H066, anticorps CLN11, anticorps GEP, anticorps GP88, anticorps PCDGF, anticorps PEPI, anticorps PGRN, anticorps epithelin, anticorps acrogranin, anticorps granulin precursor, anticorps granulin a, anticorps Granulins, anticorps granulin L homeolog, anticorps granulin, anticorps GRN, anticorps grna, anticorps grn, anticorps grn.L, anticorps granulin, anticorps ORF1 granulin, anticorps Grn

Sujet: Granulins are a family of secreted, glycosylated peptides that are cleaved from a single precursor protein with 7.5 repeats of a highly conserved 12-cysteine granulin/epithelin motif. The 88 kDa precursor protein, progranulin, is also called proepithelin and PC cell-derived growth factor. Cleavage of the signal peptide produces mature granulin which can be further cleaved into a variety of active, 6 kDa peptides. These smaller cleavage products are named granulin A, granulin B, granulin C, etc. Epithelins 1 and 2 are synonymous with granulins A and B, respectively. Both the peptides and intact granulin protein regulate cell growth. However, different members of the granulin protein family may act as inhibitors, stimulators, or have dual actions on cell growth. Granulin family members are important in normal development, wound healing, and tumorigenesis. [provided by RefSeq, Jul 2008],CLN11, GEP, GP88, PCDGF, PEPI, PGRN,Cancer,Cell Biology & Developmental Biology,Cytokines,Epigenetics & Nuclear Signaling,Growth factors,Immunology & Inflammation,Neurodegenerative Diseases,Neuroscience,RNA Binding,Signal Transduction,GRN

Poids moléculaire: 55,75kDa

ID gène: 2896

UniProt: P28799