IGHG1 anticorps

N° du produit ABIN7267844

Détail du produit anti-IGHG1 anticorps

Antigène: IGHG1 (Immunoglobulin Heavy Constant gamma 1 (G1m Marker) (IGHG1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp IGHG1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Fonction: Human IgG Rabbit mAb

Réactivité croisée: Humain

Attributs du produit: Monoclonal Antibodies

Purification: Affinity purification

Immunogène: A synthesized peptide derived from human Human IgG

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000,IHC,1:50 - 1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur IGHG1

Antigène: IGHG1 (Immunoglobulin Heavy Constant gamma 1 (G1m Marker) (IGHG1))

Autre désignation: IGHG1 (IGHG1 Produits)

Synonymes: anticorps RGD1359539, anticorps IgG1, anticorps Igh-4, anticorps VH7183, anticorps immunoglobulin heavy constant gamma 1, anticorps immunoglobulin heavy constant gamma 1 (G1m marker), anticorps Ighg1, anticorps IGHG1

Sujet: As a monomeric immunoglobulin that is predominately involved in the secondary antibody response and the only isotype that can pass through the human placenta, Immunoglobulin G (IgG) is synthesized and secreted by plasma B cells, and constitutes 75 % of serum immunoglobulins in humans. IgG antibodies protect the body against the pathogens by agglutination and immobilization, complement activation, toxin neutralization, as well as the antibody-dependent cell-mediated cytotoxicity (ADCC). IgG tetramer contains two heavy chains (50 kDa ) and two light chains (25 kDa) linked by disulfide bonds, that is the two identical halves form the Y-like shape. IgG is digested by pepsin proteolysis into Fab fragment (antigen-binding fragment) and Fc fragment ("crystallizable" fragment). IgG1 is most abundant in serum among the four IgG subclasses (IgG1, 2, 3 and 4) and binds to Fc receptors (FcγR ) on phagocytic cells with high affinity.,Immunology & Inflammation,IGHG1

Poids moléculaire: 52kDa

ID gène: 3500

UniProt: P01857, P01859, P01860, P01861