The ITGB3 protein product is the integrin beta chain beta 3. Integrins are integral cell-surface proteins composed of an alpha chain and a beta chain. A given chain may combine with multiple partners resulting in different integrins. Integrin beta 3 is found along with the alpha IIb chain in platelets. Integrins are known to participate in cell adhesion as well as cell-surface mediated signalling. [provided by RefSeq, Jul 2008],BDPLT16,BDPLT2,CD61,GP3A,GPIIIa,GT,Integrin beta 3,ITGB3,Angiogenesis,Blood,Cancer,Cardiovascular,Cardiovascular diseases,Cardiovascular diseases_Hypertension,CDs,Cell Adhesion,Cell Biology & Developmental Biology,Cytoskeleton,G protein signaling,G protein signaling_G-Protein-Coupled Receptors Signaling to MAPK/Erk,Immunology & Inflammation,Invasion and Metastasis,MAPK-Erk Signaling Pathway,PI3K-Akt Signaling Pathway,Signal Transduction,ITGB3