KSR1 anticorps (AA 320-420)
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- Antigène Voir toutes KSR1 Anticorps
- KSR1 (Kinase Suppressor of Ras 1 (KSR1))
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Épitope
- AA 320-420
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp KSR1 est non-conjugé
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Application
- Western Blotting (WB), Immunofluorescence (IF)
- Fonction
- KSR1 Rabbit pAb
- Séquence
- SSPAPFPTSS NPSSATTPPN PSPGQRDSRF NFPAAYFIHH RQQFIFPVPS AGHCWKCLLI AESLKENAFN ISAFAHAAPL PEAADGTRLD DQPKADVLEA H
- Réactivité croisée
- Humain, Souris, Rat
- Attributs du produit
- Polyclonal Antibodies
- Purification
- Affinity purification
- Immunogène
- Recombinant fusion protein containing a sequence corresponding to amino acids 320-420 of human KSR1 (NP_055053.1).
- Isotype
- IgG
- Top Product
- Discover our top product KSR1 Anticorps primaire
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- Indications d'application
- WB,1:500 - 1:2000,IF,1:50 - 1:100
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20°C. Avoid freeze / thaw cycles.
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- Antigène
- KSR1 (Kinase Suppressor of Ras 1 (KSR1))
- Autre désignation
- KSR1 (KSR1 Produits)
- Sujet
- Part of a multiprotein signaling complex which promotes phosphorylation of Raf family members and activation of downstream MAP kinases (By similarity. Independently of its kinase activity, acts as MAP2K1/MEK1 and MAP2K2/MEK2-dependent allosteric activator of BRAF, upon binding to MAP2K1/MEK1 or MAP2K2/MEK2, dimerizes with BRAF and promotes BRAF-mediated phosphorylation of MAP2K1/MEK1 and/or MAP2K2/MEK2. Promotes activation of MAPK1 and/or MAPK3, both in response to EGF and to cAMP (By similarity. Its kinase activity is unsure (By similarity. Some protein kinase activity has been detected in vitro, however the physiological relevance of this activity is unknown (By similarity.,KSR1,KSR,RSU2,Signal Transduction,G protein signaling,G2/M DNA Damage Checkpoint,Kinase,Serine/threonine kinases,Tyrosine kinases,MAPK-Erk Signaling Pathway,KSR1
- Poids moléculaire
- 84kDa/87kDa/97kDa/102kDa
- ID gène
- 8844
- UniProt
- Q8IVT5
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