Laminin gamma 1 anticorps (AA 1300-1609)

N° du produit ABIN7268186

Détail du produit anti-Laminin gamma 1 anticorps

Antigène: Laminin gamma 1 (LAMC1) (Laminin, gamma 1 (LAMC1))

Épitope: AA 1300-1609

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Laminin gamma 1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Fonction: LAMC1 Rabbit pAb

Séquence: IDQKLKDYED LREDMRGKEL EVKNLLEKGK TEQQTADQLL ARADAAKALA EEAAKKGRDT LQEANDILNN LKDFDRRVND NKTAAEEALR KIPAINQTIT EANEKTREAQ QALGSAAADA TEAKNKAHEA ERIASAVQKN ATSTKAEAER TFAEVTDLDN EVNNMLKQLQ EAEKELKRKQ DDADQDMMMA GMASQAAQEA EINARKAKNS VTSLLSIIND LLEQLGQLDT VDLNKLNEIE GTLNKAKDEM KVSDLDRKVS DLENEAKKQE AAIMDYNRDI EEIMKDIRNL EDIRKTLPSG CFNTPSIEKP

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Polyclonal Antibodies

Purification: Affinity purification

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 1300-1609 of human LAMC1 (NP_002284.3).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000,IHC,1:50 - 1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur Laminin gamma 1

Antigène: Laminin gamma 1 (LAMC1) (Laminin, gamma 1 (LAMC1))

Autre désignation: LAMC1 (LAMC1 Produits)

Synonymes: anticorps lamb2, anticorps Lamb2, anticorps B2e, anticorps sly, anticorps LAMB2, anticorps putative laminin gamma-1 chain, anticorps laminin subunit gamma 1, anticorps laminin, gamma 1, anticorps Smp_163810, anticorps lamc1, anticorps Lamc1, anticorps LAMC1

Sujet: Laminins, a family of extracellular matrix glycoproteins, are the major noncollagenous constituent of basement membranes. They have been implicated in a wide variety of biological processes including cell adhesion, differentiation, migration, signaling, neurite outgrowth and metastasis. Laminins, composed of 3 non identical chains: laminin alpha, beta and gamma. Some of the chains have been shown to differ with respect to their tissue distribution, presumably reflecting diverse functions in vivo. This gene encodes the gamma chain isoform laminin, gamma 1. The gamma 1 chain, formerly thought to be a beta chain, contains structural domains similar to beta chains, however, lacks the short alpha region separating domains I and II. The structural organization of this gene also suggested that it had diverged considerably from the beta chain genes. Embryos of transgenic mice in which both alleles of the gamma 1 chain gene were inactivated by homologous recombination, lacked basement membranes, indicating that laminin, gamma 1 chain is necessary for laminin heterotrimer assembly. It has been inferred by analogy with the strikingly similar 3' UTR sequence in mouse laminin gamma 1 cDNA, that multiple polyadenylation sites are utilized in human to generate the 2 different sized mRNAs (5.5 and 7.5 kb) seen on Northern analysis.,LAMC1,LAMB2,Signal Transduction,Cell Biology & Developmental Biology,Cell Adhesion,Cytoskeleton,Neuroscience,Neurodegenerative Diseases,LAMC1

Poids moléculaire: 177kDa

ID gène: 3915

UniProt: P11047