MASP2 anticorps (AA 445-686)

N° du produit ABIN7268387

Détail du produit anti-MASP2 anticorps

Antigène: MASP2 (Mannan-Binding Lectin serine Peptidase 2 (MASP2))

Épitope: AA 445-686

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MASP2 est non-conjugé

Application: Western Blotting (WB)

Fonction: MASP2 Rabbit pAb

Séquence: IYGGQKAKPG DFPWQVLILG GTTAAGALLY DNWVLTAAHA VYEQKHDASA LDIRMGTLKR LSPHYTQAWS EAVFIHEGYT HDAGFDNDIA LIKLNNKVVI NSNITPICLP RKEAESFMRT DDIGTASGWG LTQRGFLARN LMYVDIPIVD HQKCTAAYEK PPYPRGSVTA NMLCAGLESG GKDSCRGDSG GALVFLDSET ERWFVGGIVS WGSMNCGEAG QYGVYTKVIN YIPWIENIIS DF

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Polyclonal Antibodies

Purification: Affinity purification

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 445-686 of human MASP2 (NP_006601.2).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur MASP2

Antigène: MASP2 (Mannan-Binding Lectin serine Peptidase 2 (MASP2))

Autre désignation: MASP2 (MASP2 Produits)

Synonymes: anticorps MAP19, anticorps MASP-2, anticorps MASP1P1, anticorps sMAP, anticorps MAp19, anticorps mannan binding lectin serine peptidase 2, anticorps mannan-binding lectin serine peptidase 2, anticorps MASP2, anticorps Masp2

Sujet: This gene encodes a member of the peptidase S1 family of serine proteases. The encoded preproprotein is proteolytically processed to generate A and B chains that heterodimerize to form the mature protease. This protease cleaves complement components C2 and C4 in order to generate C3 convertase in the lectin pathway of the complement system. The encoded protease also plays a role in the coagulation cascade through cleavage of prothrombin to form thrombin. Myocardial infarction and acute stroke patients exhibit reduced serum concentrations of the encoded protein. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed.,MASP2,MAP19,MASP-2,MASP1P1,sMAP,Immunology & Inflammation,Cell Intrinsic Innate Immunity Signaling Pathway,Cardiovascular,Blood,Serum Proteins,MASP2

Poids moléculaire: 20kDa/75kDa

ID gène: 10747

UniProt: O00187

Pathways: Système du Complément