MTA1 anticorps (AA 600-700)

N° du produit ABIN7268485

Détail du produit anti-MTA1 anticorps

Antigène: MTA1 (Metastasis Associated 1 (MTA1))

Épitope: AA 600-700

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MTA1 est non-conjugé

Application: Western Blotting (WB)

Fonction: MTA1 Rabbit pAb

Séquence: LMPSRGLANH GQARHMGPSR NLLLNGKSYP TKVRLIRGGS LPPVKRRRMN WIDAPDDVFY MATEETRKIR KLLSSSETKR AARRPYKPIA LRQSQALPPR P

Réactivité croisée: Humain, Souris

Attributs du produit: Polyclonal Antibodies

Purification: Affinity purification

Immunogène: A synthetic peptide corresponding to a sequence within amino acids 600-700 of human MTA1 (NP_004680.2).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur MTA1

Antigène: MTA1 (Metastasis Associated 1 (MTA1))

Autre désignation: MTA1 (MTA1 Produits)

Synonymes: anticorps Tex22, anticorps metastasis associated 1, anticorps metastasis associated 1 L homeolog, anticorps MTA1, anticorps Mta1, anticorps mta1.L

Sujet: This gene encodes a protein that was identified in a screen for genes expressed in metastatic cells, specifically, mammary adenocarcinoma cell lines. Expression of this gene has been correlated with the metastatic potential of at least two types of carcinomas although it is also expressed in many normal tissues. The role it plays in metastasis is unclear. It was initially thought to be the 70kD component of a nucleosome remodeling deacetylase complex, NuRD, but it is more likely that this component is a different but very similar protein. These two proteins are so closely related, though, that they share the same types of domains. These domains include two DNA binding domains, a dimerization domain, and a domain commonly found in proteins that methylate DNA. The profile and activity of this gene product suggest that it is involved in regulating transcription and that this may be accomplished by chromatin remodeling. Two transcript variants encoding different isoforms have been found for this gene.,MTA1,Epigenetics & Nuclear Signaling,MTA1

Poids moléculaire: 49kDa/79kDa/80kDa

ID gène: 9112

UniProt: Q13330

Pathways: Chromatin Binding