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c-MYC anticorps

KO Validated MYC Reactivité: Humain WB, IF, ChIP Hôte: Lapin Monoclonal unconjugated
N° du produit ABIN7268711
  • Antigène Voir toutes c-MYC (MYC) Anticorps
    c-MYC (MYC) (Myc Proto-Oncogene protein (MYC))
    Reactivité
    • 359
    • 162
    • 115
    • 16
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    • 13
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    • 1
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    Humain
    Hôte
    • 277
    • 99
    • 7
    • 5
    • 3
    • 1
    Lapin
    Clonalité
    • 271
    • 120
    Monoclonal
    Conjugué
    • 190
    • 31
    • 24
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    • 8
    • 8
    • 5
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    • 1
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    Cet anticorp c-MYC est non-conjugé
    Application
    • 286
    • 136
    • 94
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    Western Blotting (WB), Immunofluorescence (IF), Chromatin Immunoprecipitation (ChIP)
    Fonction
    [KO Validated] c-Myc Rabbit mAb
     Réactivité croisée
    Humain, Souris
    Attributs du produit
    Monoclonal Antibodies
    Purification
    Affinity purification
    Classe de qualité
    KO Validated
    Immunogène
    A synthesized peptide derived from human c-Myc
    Isotype
    IgG
    Top Product
    Discover our top product MYC Anticorps primaire
  • Indications d'application
    WB,1:500 - 1:2000,IF,1:50 - 1:200,ChIP,1:50 - 1:200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C. Avoid freeze / thaw cycles.
  • Antigène
    c-MYC (MYC) (Myc Proto-Oncogene protein (MYC))
    Autre désignation
    MYC (MYC Produits)
    Sujet
    The protein encoded by this gene is a multifunctional, nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. It functions as a transcription factor that regulates transcription of specific target genes. Mutations, overexpression, rearrangement and translocation of this gene have been associated with a variety of hematopoietic tumors, leukemias and lymphomas, including Burkitt lymphoma. There is evidence to show that alternative translation initiations from an upstream, in-frame non-AUG (CUG) and a downstream AUG start site result in the production of two isoforms with distinct N-termini. The synthesis of non-AUG initiated protein is suppressed in Burkitt's lymphomas, suggesting its importance in the normal function of this gene. [provided by RefSeq, Jul 2008],MRTL;MYCC;bHLHe39;c-Myc;MYC,Apoptosis,Cancer,Cell Biology & Developmental Biology,Cell Cycle,Cell Cycle_Cell differentiation,Endocrine & Metabolism,Epigenetics & Nuclear Signaling,G1/S Checkpoint,Hedgehog Signaling Pathway,IL-6 Receptor Signaling Pathway,Immunology & Inflammation,MAPK-Erk Signaling Pathway,MAPK-P38 Signaling Pathway,Notch Signaling Pathway,Protein phosphorylation,Signal Transduction,Stem Cells,Transcription Factors,Tumor biomarkers,Warburg Effect,MYC
    Poids moléculaire
    57kDa
    ID gène
    4609
    UniProt
    P01106
    Pathways
    Signalisation p53, Cycle Cellulaire, Sensory Perception of Sound, Transition Metal Ion Homeostasis, Mitotic G1-G1/S Phases, Positive Regulation of Endopeptidase Activity, Regulation of Carbohydrate Metabolic Process, Positive Regulation of Response to DNA Damage Stimulus, L'effet Warburg
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