NECAB3 anticorps (AA 1-362)

N° du produit ABIN7268789

Détail du produit anti-NECAB3 anticorps

Antigène: NECAB3 (N-Terminal EF-Hand Calcium Binding Protein 3 (NECAB3))

Épitope: AA 1-362

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NECAB3 est non-conjugé

Application: Western Blotting (WB)

Fonction: NECAB3 Rabbit pAb

Séquence: MACAGLLTVC LLRPPAPQPQ PQTPRHPQLA PDPGPAGHTL FQDVFRRADK NDDGKLSFEE FQNYFADGVL SLGELQELFS GIDGHLTDNL ETEKLCDYFS EHLGVYRPVL AALESLNRAV LAAMDATKLE YERASKVDQF VTRFLLRETV SQLQALQSSL EGASDTLEAQ AHGWRSDAES VEAQSRLCGS RRAGRRALRS VSRSSTWSPG SSDTGRSSEA EMQWRLQVNR LQELIDQLEC KAPRLEPLRE EDLAKGPDLH ILMAQRQVQV AEEGLQDFHR ALRCYVDFTG AQSHCLHVSA QKMLDGASFT LYEFWQDEAS WRRHQQSPGS KAFQRILIDH LRAPDTLTTV FFPASWWIMN NN

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Polyclonal Antibodies

Purification: Affinity purification

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 1-362 of human NECAB3 (NP_112508.3).

Isotype: IgG

Information d'application

Indications d'application: WB,1:200 - 1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur NECAB3

Antigène: NECAB3 (N-Terminal EF-Hand Calcium Binding Protein 3 (NECAB3))

Autre désignation: NECAB3 (NECAB3 Produits)

Synonymes: anticorps Apba2bp, anticorps APBA2BP, anticorps NECAB3, anticorps EFCBP3, anticorps NIP1, anticorps STIP3, anticorps SYTIP2, anticorps XB51, anticorps dJ63M2.4, anticorps dJ63M2.5, anticorps 2900010M17Rik, anticorps AI853434, anticorps Nip1, anticorps N-terminal EF-hand calcium binding protein 3, anticorps Necab3, anticorps NECAB3

Sujet: The protein encoded by this gene interacts with the amino-terminal domain of the neuron-specific X11-like protein (X11L), inhibits the association of X11L with amyloid precursor protein through a non-competitive mechanism, and abolishes the suppression of beta-amyloid production by X11L. This protein, together with X11L, may play an important role in the regulatory system of amyloid precursor protein metabolism and beta-amyloid generation. The protein is phosphorylated by NIMA-related expressed kinase 2, and localizes to the Golgi apparatus. Multiple transcript variants encoding different isoforms have been found for this gene.,NECAB3,APBA2BP,EFCBP3,NIP1,STIP3,SYTIP2,XB51,dJ63M2.4,dJ63M2.5,Neuroscience,Neurodegenerative Diseases,Amyloid Plaque and Neurofibrillary Tangle Formation in Alzheimer's Disease,NECAB3

Poids moléculaire: 22kDa/40kDa/44kDa

ID gène: 63941

UniProt: Q96P71