Neuregulin 3 anticorps
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- Antigène Voir toutes Neuregulin 3 (NRG3) Anticorps
- Neuregulin 3 (NRG3)
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp Neuregulin 3 est non-conjugé
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Application
- Western Blotting (WB)
- Fonction
- Neuregulin-3 (NRG3) Rabbit mAb
- Réactivité croisée
- Humain, Souris, Rat
- Attributs du produit
- Monoclonal Antibodies
- Purification
- Affinity purification
- Immunogène
- A synthesized peptide derived from human Neuregulin-3 (Neuregulin-3 (NRG3))
- Isotype
- IgG
- Top Product
- Discover our top product NRG3 Anticorps primaire
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- Indications d'application
- WB,1:500 - 1:2000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20°C. Avoid freeze / thaw cycles.
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- Antigène
- Neuregulin 3 (NRG3)
- Autre désignation
- NRG3 (NRG3 Produits)
- Synonymes
- anticorps NRG3, anticorps HRG3, anticorps pro-NRG3, anticorps ska, anticorps RGD1559678, anticorps neuregulin 3, anticorps pro-neuregulin-3, membrane-bound isoform, anticorps NRG3, anticorps nrg3, anticorps LOC100478170, anticorps Nrg3
- Sujet
- This gene is a member of the neuregulin gene family. This gene family encodes ligands for the transmembrane tyrosine kinase receptors ERBB3 and ERBB4 - members of the epidermal growth factor receptor family. Ligand binding activates intracellular signaling cascades and the induction of cellular responses including proliferation, migration, differentiation, and survival or apoptosis. This gene encodes neuregulin 3 (NRG3). NRG3 has been shown to activate the tyrosine phosphorylation of its cognate receptor, ERBB4, and is thought to influence neuroblast proliferation, migration and differentiation by signalling through ERBB4. NRG3 also promotes mammary differentiation during embryogenesis. Linkage studies have implicated this gene as a susceptibility locus for schizophrenia and schizoaffective disorder. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional transcript variants have been described but their biological validity has not been verified.[provided by RefSeq, Sep 2009],HRG3, pro-NRG3,Cancer,ErbB-HER Signaling Pathway,Neuroscience,Signal Transduction,NRG3
- Poids moléculaire
- 56kDa
- ID gène
- 10718
- UniProt
- P56975
- Pathways
- Signalisation RTK
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