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NGEF anticorps (AA 429-710)

NGEF Reactivité: Humain WB, IHC, IF Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN7268882
  • Antigène Voir toutes NGEF Anticorps
    NGEF (Neuronal Guanine Nucleotide Exchange Factor (NGEF))
    Épitope
    • 15
    • 15
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 429-710
    Reactivité
    • 41
    • 41
    • 33
    • 3
    • 3
    • 3
    • 3
    Humain
    Hôte
    • 47
    • 1
    Lapin
    Clonalité
    • 47
    • 1
    Polyclonal
    Conjugué
    • 7
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp NGEF est non-conjugé
    Application
    • 38
    • 26
    • 26
    • 11
    • 6
    • 6
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
    Fonction
    NGEF Rabbit pAb
    Séquence
    RVEERSEREC TALDAHKELE MVVKACNEGV RKMSRTEQMI SIQKKMEFKI KSVPIISHSR WLLKQGELQQ MSGPKTSRTL RTKKLFHEIY LFLFNDLLVI CRQIPGDKYQ VFDSAPRGLL RVEELEDQGQ TLANVFILRL LENADDREAT YMLKASSQSE MKRWMTSLAP NRRTKFVSFT SRLLDCPQVQ CVHPYVAQQP DELTLELADI LNILDKTDDG WIFGERLHDQ ERGWFPSSMT EEILNPKIRS QNLKECFRVH KMDDPQRSQN KDRRKLGSRN RQ
     Réactivité croisée
    Humain, Souris, Rat
    Attributs du produit
    Polyclonal Antibodies
    Purification
    Affinity purification
    Immunogène
    Recombinant fusion protein containing a sequence corresponding to amino acids 429-710 of human NGEF (NP_062824.2).
    Isotype
    IgG
    Top Product
    Discover our top product NGEF Anticorps primaire
  • Indications d'application
    WB,1:500 - 1:2000,IHC,1:50 - 1:100,IF,1:50 - 1:100
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C. Avoid freeze / thaw cycles.
  • Antigène
    NGEF (Neuronal Guanine Nucleotide Exchange Factor (NGEF))
    Autre désignation
    NGEF (NGEF Produits)
    Synonymes
    anticorps Ephexin-1, anticorps ARHGEF27, anticorps EPHEXIN, anticorps Tims2, anticorps ephexin, anticorps Besh3, anticorps ephexin-1, anticorps neuronal guanine nucleotide exchange factor, anticorps NGEF, anticorps Ngef
    Sujet
    Acts as a guanine nucleotide exchange factor (GEF which differentially activates the GTPases RHOA, RAC1 and CDC42. Plays a role in axon guidance regulating ephrin-induced growth cone collapse and dendritic spine morphogenesis. Upon activation by ephrin through EPHA4, the GEF activity switches toward RHOA resulting in its activation. Activated RHOA promotes cone retraction at the expense of RAC1- and CDC42-stimulated growth cone extension (By similarity.,NGEF,ARHGEF27,EPHEXIN,ephexin-1,Signal Transduction,G protein signaling,Signal Transduction,Neuroscience,NGEF
    Poids moléculaire
    26kDa/71kDa/82kDa
    ID gène
    25791
    UniProt
    Q8N5V2
    Pathways
    Neurotrophin Signaling Pathway
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