NGEF anticorps (AA 429-710)
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- Antigène Voir toutes NGEF Anticorps
- NGEF (Neuronal Guanine Nucleotide Exchange Factor (NGEF))
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Épitope
- AA 429-710
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp NGEF est non-conjugé
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Application
- Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
- Fonction
- NGEF Rabbit pAb
- Séquence
- RVEERSEREC TALDAHKELE MVVKACNEGV RKMSRTEQMI SIQKKMEFKI KSVPIISHSR WLLKQGELQQ MSGPKTSRTL RTKKLFHEIY LFLFNDLLVI CRQIPGDKYQ VFDSAPRGLL RVEELEDQGQ TLANVFILRL LENADDREAT YMLKASSQSE MKRWMTSLAP NRRTKFVSFT SRLLDCPQVQ CVHPYVAQQP DELTLELADI LNILDKTDDG WIFGERLHDQ ERGWFPSSMT EEILNPKIRS QNLKECFRVH KMDDPQRSQN KDRRKLGSRN RQ
- Réactivité croisée
- Humain, Souris, Rat
- Attributs du produit
- Polyclonal Antibodies
- Purification
- Affinity purification
- Immunogène
- Recombinant fusion protein containing a sequence corresponding to amino acids 429-710 of human NGEF (NP_062824.2).
- Isotype
- IgG
- Top Product
- Discover our top product NGEF Anticorps primaire
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- Indications d'application
- WB,1:500 - 1:2000,IHC,1:50 - 1:100,IF,1:50 - 1:100
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20°C. Avoid freeze / thaw cycles.
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- Antigène
- NGEF (Neuronal Guanine Nucleotide Exchange Factor (NGEF))
- Autre désignation
- NGEF (NGEF Produits)
- Synonymes
- anticorps Ephexin-1, anticorps ARHGEF27, anticorps EPHEXIN, anticorps Tims2, anticorps ephexin, anticorps Besh3, anticorps ephexin-1, anticorps neuronal guanine nucleotide exchange factor, anticorps NGEF, anticorps Ngef
- Sujet
- Acts as a guanine nucleotide exchange factor (GEF which differentially activates the GTPases RHOA, RAC1 and CDC42. Plays a role in axon guidance regulating ephrin-induced growth cone collapse and dendritic spine morphogenesis. Upon activation by ephrin through EPHA4, the GEF activity switches toward RHOA resulting in its activation. Activated RHOA promotes cone retraction at the expense of RAC1- and CDC42-stimulated growth cone extension (By similarity.,NGEF,ARHGEF27,EPHEXIN,ephexin-1,Signal Transduction,G protein signaling,Signal Transduction,Neuroscience,NGEF
- Poids moléculaire
- 26kDa/71kDa/82kDa
- ID gène
- 25791
- UniProt
- Q8N5V2
- Pathways
- Neurotrophin Signaling Pathway
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