NLRP10 anticorps (AA 1-300)

N° du produit ABIN7268936

Détail du produit anti-NLRP10 anticorps

Antigène: NLRP10 (NLR Family, Pyrin Domain Containing 10 (NLRP10))

Épitope: AA 1-300

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NLRP10 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF)

Fonction: NLRP10 Rabbit pAb

Séquence: MAMAKARKPR EALLWALSDL EENDFKKLKF YLRDMTLSEG QPPLARGELE GLIPVDLAEL LISKYGEKEA VKVVLKGLKV MNLLELVDQL SHICLHDYRE VYREHVRCLE EWQEAGVNGR YNQVLLVAKP SSESPESLAC PFPEQELESV TVEALFDSGE KPSLAPSLVV LQGSAGTGKT TLARKMVLDW ATGTLYPGRF DYVFYVSCKE VVLLLESKLE QLLFWCCGDN QAPVTEILRQ PERLLFILDG FDELQRPFEE KLKKRGLSPK ESLLHLLIRR HTLPTCSLLI TTRPLALRNL

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Polyclonal Antibodies

Purification: Affinity purification

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human NLRP10 (NP_789791.1).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000,IF,1:50 - 1:100

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur NLRP10

Antigène: NLRP10 (NLR Family, Pyrin Domain Containing 10 (NLRP10))

Autre désignation: NLRP10 (NLRP10 Produits)

Synonymes: anticorps CLR11.1, anticorps NALP10, anticorps NOD8, anticorps PAN5, anticorps PYNOD, anticorps 6430548I20Rik, anticorps Nalp10, anticorps Napl10, anticorps Pynod, anticorps NLR family pyrin domain containing 10, anticorps NLR family, pyrin domain containing 10, anticorps NLRP10, anticorps Nlrp10

Sujet: Members of the NALP protein family typically contain a NACHT domain, a NACHT-associated domain (NAD), a C-terminal leucine-rich repeat (LRR) region, and an N-terminal pyrin domain (PYD). The protein encoded by this gene belongs to the NALP protein family despite lacking the LRR region. This protein likely plays a regulatory role in the innate immune system. The protein belongs to the signal-induced multiprotein complex, the inflammasome, that activates the pro-inflammatory caspases, caspase-1 and caspase-5. Other experiments indicate that this gene acts as a multifunctional negative regulator of inflammation and apoptosis.,NLRP10,CLR11.1,NALP10,NOD8,PAN5,PYNOD,Cell Biology & Developmental Biology,Apoptosis,Caspases,Immunology & Inflammation,Cytokines,Interleukins,Cell Intrinsic Innate Immunity Signaling Pathway,NLRP10

Poids moléculaire: 75kDa

ID gène: 338322

UniProt: Q86W26

Pathways: Inflammasome