NLRP12 anticorps (AA 862-1062)

N° du produit ABIN7268938

Détail du produit anti-NLRP12 anticorps

Antigène: NLRP12 (NLR Family, Pyrin Domain Containing 12 (NLRP12))

Épitope: AA 862-1062

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NLRP12 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Fonction: NLRP12 Rabbit pAb

Séquence: LWLKICRLTA AACDELASTL SVNQSLRELD LSLNELGDLG VLLLCEGLRH PTCKLQTLRL GICRLGSAAC EGLSVVLQAN HNLRELDLSF NDLGDWGLWL LAEGLQHPAC RLQKLWLDSC GLTAKACENL YFTLGINQTL TDLYLTNNAL GDTGVRLLCK RLSHPGCKLR VLWLFGMDLN KMTHSRLAAL RVTKPYLDIG C

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Polyclonal Antibodies

Purification: Affinity purification

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 862-1062 of human NLRP12 (NP_001264055.1).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000,IHC,1:50 - 1:100,IF,1:50 - 1:100

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur NLRP12

Antigène: NLRP12 (NLR Family, Pyrin Domain Containing 12 (NLRP12))

Autre désignation: NLRP12 (NLRP12 Produits)

Synonymes: anticorps Nalp12, anticorps NALP12, anticorps CLR19.3, anticorps FCAS2, anticorps PAN6, anticorps PYPAF7, anticorps RNO, anticorps RNO2, anticorps NLR family, pyrin domain containing 12, anticorps NLR family pyrin domain containing 12, anticorps NACHT, LRR and PYD domains-containing protein 3, anticorps Nlrp12, anticorps NLRP12, anticorps LOC100018508

Sujet: This gene encodes a member of the CATERPILLER family of cytoplasmic proteins. The encoded protein, which contains an N-terminal pyrin domain, a NACHT domain, a NACHT-associated domain, and a C-terminus leucine-rich repeat region, functions as an attenuating factor of inflammation by suppressing inflammatory responses in activated monocytes. Mutations in this gene cause familial cold autoinflammatory syndrome type 2. Alternative splicing results in multiple transcript variants.,NLRP12,CLR19.3,FCAS2,NALP12,PAN6,PYPAF7,RNO,RNO2,Signal Transduction,Cell Biology & Developmental Biology,Apoptosis,Caspases,NLRP12

Poids moléculaire: 31kDa/101kDa/107kDa/113kDa/114kDa/120kDa

ID gène: 91662

UniProt: P59046

Pathways: Positive Regulation of Endopeptidase Activity, Inflammasome