The protein encoded by this gene acts as a transcriptional coactivator for steroid and nuclear hormone receptors. It is a member of the p160/steroid receptor coactivator (SRC) family and like other family members has histone acetyltransferase activity and contains a nuclear localization signal, as well as bHLH and PAS domains. The product of this gene binds nuclear receptors directly and stimulates the transcriptional activities in a hormone-dependent fashion. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008],F-SRC-1, KAT13A, RIP160, SRC1, bHLHe42, bHLHe74,Cancer,Endocrine & Metabolism,Epigenetic writers and erasers of core Histones,Epigenetic writers and erasers of core Histones_Acetylation,Epigenetics & Nuclear Signaling,Lipid Metabolism,Nuclear Receptor Signaling,Nuclear Receptor Signaling_Nuclear hormone receptors,Signal Transduction,NCOA1