PANK2 anticorps (AA 300-400)

N° du produit ABIN7269169

Détail du produit anti-PANK2 anticorps

Antigène: PANK2 (Pantothenate Kinase 2 (PANK2))

Épitope: AA 300-400

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PANK2 est non-conjugé

Application: Western Blotting (WB)

Fonction: PANK2 Rabbit pAb

Réactivité croisée: Souris

Attributs du produit: Polyclonal Antibodies

Purification: Affinity purification

Immunogène: A synthetic peptide corresponding to a sequence within amino acids 300-400 of human PANK2 (NP_705902.2).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur PANK2

Antigène: PANK2 (Pantothenate Kinase 2 (PANK2))

Autre désignation: PANK2 (PANK2 Produits)

Synonymes: anticorps ATPANK2, anticorps F10M6.180, anticorps F10M6_180, anticorps pantothenate kinase 2, anticorps PANK2, anticorps C20orf48, anticorps HARP, anticorps HSS, anticorps NBIA1, anticorps PKAN, anticorps 4933409I19Rik, anticorps AI642621, anticorps pantothenate kinase 2, anticorps pantothenate kinase 2, mitochondrial, anticorps ribonuclease A family member 11 (inactive), anticorps PANK2, anticorps Tsp_01576, anticorps LOC100539295, anticorps Pank2, anticorps RNASE11

Sujet: This gene encodes a protein belonging to the pantothenate kinase family and is the only member of that family to be expressed in mitochondria. Pantothenate kinase is a key regulatory enzyme in the biosynthesis of coenzyme A (CoA) in bacteria and mammalian cells. It catalyzes the first committed step in the universal biosynthetic pathway leading to CoA and is itself subject to regulation through feedback inhibition by acyl CoA species. Mutations in this gene are associated with HARP syndrome and pantothenate kinase-associated neurodegeneration (PKAN), formerly Hallervorden-Spatz syndrome. Alternative splicing, involving the use of alternate first exons, results in multiple transcripts encoding different isoforms. [provided by RefSeq, Jul 2008],C20orf48,HARP,HSS,NBIA1,PKAN,PANK2,Endocrine & Metabolism,Neurodegenerative Diseases,Neuroscience,Signal Transduction,PANK2

ID gène: 80025

UniProt: Q9BZ23

Pathways: Ribonucleoside Biosynthetic Process