C14orf166 anticorps (AA 151-244) (Biotin)

N° du produit ABIN717418

Détail du produit anti-C14orf166 anticorps (Biotin)

Antigène: C14orf166 (Chromosome 14 Open Reading Frame 166 (C14orf166))

Épitope: AA 151-244

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp C14orf166 est conjugé à/à la Biotin

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro))

Réactivité croisée: Humain

Homologie: Mouse,Rat,Dog,Cow,Sheep,Pig,Chicken,Rabbit

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human RLLM1/C14orf166

Isotype: IgG

Information d'application

Indications d'application: IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C for 12 months.

Date de péremption: 12 months

Détails sur C14orf166

Antigène: C14orf166 (Chromosome 14 Open Reading Frame 166 (C14orf166))

Autre désignation: RLLM1 (C14orf166 Produits)

Synonymes: anticorps CGI99, anticorps CLE, anticorps CLE7, anticorps LCRP369, anticorps RLLM1, anticorps C14orf166, anticorps C10H14orf166, anticorps RNA transcription, translation and transport factor, anticorps chromosome 5 C14orf166 homolog, anticorps RNA transcription, translation and transport factor S homeolog, anticorps zgc:56576, anticorps RTRAF, anticorps C5H14orf166, anticorps rtraf.S, anticorps zgc:56576

Sujet:

Synonyms: CGI 99, CGI99, CLE, Homeobox prox 1, RLLM1, Chromosome 14 open reading frame 166, CLE7, LCRP369, RLL mot containing 1, CN166_HUMAN.

Background: CGI-99 is a 244 amino acid protein that localizes to the nucleus, as well as to the cytoplasm, and belongs to the UPF0568 family. Expressed in a variety of tissues with particularly high levels in heart and skeletal muscle, CGI-99 functions as a homodimer that interacts with Ninein and is thought to regulate Ninein function. CGI-99 is overexpressed in brain tumor tissue, suggesting a role in tumor development and metastasis. The gene encoding CGI-99 maps to human chromosome 14, which houses over 700 genes and comprises nearly 3.5 % of the human genome. Chromosome 14 encodes the presinilin 1 (PSEN1) gene, which is one of the three key genes associated with the development of Alzheimer's disease (AD). The SERPINA1 gene is also located on chromosome 14 and, when defective, leads to the genetic disorder ?-antitrypsin deficiency, which is characterized by severe lung complications and liver dysfunction.

ID gène: 51637