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Phospholamban anticorps (pSer16, pThr17)

PLN Reactivité: Humain WB Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN7269330
  • Antigène Voir toutes Phospholamban (PLN) Anticorps
    Phospholamban (PLN)
    Épitope
    • 24
    • 17
    • 11
    • 9
    • 8
    • 6
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    pSer16, pThr17
    Reactivité
    • 79
    • 20
    • 19
    • 3
    • 2
    • 2
    • 2
    Humain
    Hôte
    • 79
    • 1
    • 1
    Lapin
    Clonalité
    • 79
    • 2
    Polyclonal
    Conjugué
    • 34
    • 6
    • 5
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    Cet anticorp Phospholamban est non-conjugé
    Application
    • 34
    • 26
    • 26
    • 25
    • 13
    • 10
    • 9
    • 9
    • 7
    • 6
    • 6
    • 4
    • 1
    • 1
    Western Blotting (WB)
    Fonction
    Phospho-PLN-S16/T17 Rabbit pAb
     Réactivité croisée
    Humain, Souris, Rat
    Attributs du produit
    Phosphorylated Antibodies
    Purification
    Affinity purification
    Immunogène
    A synthetic phosphorylated peptide around of human Phospho-PLN-S16/T17.
    Isotype
    IgG
    Top Product
    Discover our top product PLN Anticorps primaire
  • Indications d'application
    WB,1:500 - 1:2000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C. Avoid freeze / thaw cycles.
  • Antigène
    Phospholamban (PLN)
    Autre désignation
    PLN (PLN Produits)
    Sujet
    The protein encoded by this gene is found as a pentamer and is a major substrate for the cAMP-dependent protein kinase in cardiac muscle. The encoded protein is an inhibitor of cardiac muscle sarcoplasmic reticulum Ca(2+)-ATPase in the unphosphorylated state, but inhibition is relieved upon phosphorylation of the protein. The subsequent activation of the Ca(2+) pump leads to enhanced muscle relaxation rates, thereby contributing to the inotropic response elicited in heart by beta-agonists. The encoded protein is a key regulator of cardiac diastolic function. Mutations in this gene are a cause of inherited human dilated cardiomyopathy with refractory congestive heart failure, and also familial hypertrophic cardiomyopathy.,CMD1P,CMH18,PLB,PLN,Cancer,Signal Transduction,Endocrine & Metabolism,Neuroscience,Calcium Signaling,Cardiovascular,Heart,Contractility,PLN
    Poids moléculaire
    6kDa
    ID gène
    5350
    UniProt
    P26678
    Pathways
    Negative Regulation of Transporter Activity
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