PEN2 anticorps
-
- Antigène Voir toutes PEN2 (PSENEN) Anticorps
- PEN2 (PSENEN) (Presenilin Enhancer 2 Homolog (PSENEN))
-
Reactivité
- Humain
-
Hôte
- Lapin
-
Clonalité
- Monoclonal
-
Conjugué
- Cet anticorp PEN2 est non-conjugé
-
Application
- Western Blotting (WB), Immunofluorescence (IF)
- Fonction
- PEN2/PSENEN Rabbit mAb
- Réactivité croisée
- Humain, Souris, Rat
- Attributs du produit
- Monoclonal Antibodies
- Purification
- Affinity purification
- Immunogène
- A synthesized peptide derived from human PEN2/PSENEN
- Isotype
- IgG
- Top Product
- Discover our top product PSENEN Anticorps primaire
-
-
- Indications d'application
- WB,1:500 - 1:2000,IF,1:50 - 1:200
- Restrictions
- For Research Use only
-
- Format
- Liquid
- Buffer
- PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20°C. Avoid freeze / thaw cycles.
-
- Antigène
- PEN2 (PSENEN) (Presenilin Enhancer 2 Homolog (PSENEN))
- Autre désignation
- PSENEN (PSENEN Produits)
- Synonymes
- anticorps MSTP064, anticorps PEN-2, anticorps PEN2, anticorps Psenen, anticorps ACYPI006208, anticorps 1700023M09Rik, anticorps Pen-2, anticorps RGD1312037, anticorps CG33198, anticorps Dmel\\CG33198, anticorps anon-AE003800.1, anticorps dPen-2, anticorps psenen, anticorps pen-2, anticorps pen2, anticorps zgc:109727, anticorps presenilin enhancer gamma-secretase subunit, anticorps presenilin enhancer 2, anticorps presenilin enhancer gamma secretase subunit, anticorps Gamma-secretase subunit pen-2, anticorps presenilin enhancer, anticorps presenilin enhancer gamma secretase subunit S homeolog, anticorps PSENEN, anticorps PEN2, anticorps Psenen, anticorps pen-2, anticorps psenen.S, anticorps psenen
- Sujet
- Presenilins, which are components of the gamma-secretase protein complex, are required for intramembranous processing of some type I transmembrane proteins, such as the Notch proteins and the beta-amyloid precursor protein. Signaling by Notch receptors mediates a wide range of developmental cell fates. Processing of the beta-amyloid precursor protein generates neurotoxic amyloid beta peptides, the major component of senile plaques associated with Alzheimer's disease. This gene encodes a protein that is required for Notch pathway signaling, and for the activity and accumulation of gamma-secretase. Mutations resulting in haploinsufficiency for this gene cause familial acne inversa-2 (ACNINV2). Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013],MDS033, MSTP064, PEN-2, PEN2,Cell Biology & Developmental Biology,ErbB-HER Signaling Pathway,ESC Pluripotency and Differentiation,Neurodegenerative Diseases,Neurodegenerative Diseases Markers,Neurodegenerative Diseases_Amyloid Plaque and Neurofibrillary Tangle Formation in Alzheimers Disease,Neuroscience,Notch Signaling Pathway,Signal Transduction,PSENEN
- Poids moléculaire
- 13kDa
- ID gène
- 55851
- UniProt
- Q9NZ42
- Pathways
- Signalisation Notch, Neurotrophin Signaling Pathway
-