anticorps CG9927, anticorps DART6, anticorps Dmel\\CG9927, anticorps PRMT6, anticorps HRMT1L6, anticorps ARABIDOPSIS THALIANA PROTEIN ARGININE METHYLTRANSFERASE 6, anticorps ATPRMT6, anticorps protein arginine methyltransferase 6, anticorps DKFZp459B1431, anticorps Hrmt1l6, anticorps hrmt1l6, anticorps hrmt6, anticorps im:6908706, anticorps AW124876, anticorps BB233495, anticorps Arginine methyltransferase 6, anticorps protein arginine methyltransferase 6, anticorps protein arginine methyltransferase 6 S homeolog, anticorps arginine N-methyltransferase, type I, anticorps protein arginine N-methyltransferase 6, anticorps Art6, anticorps PRMT6, anticorps prmt6.S, anticorps prmt6, anticorps Prmt6
Sujet
The protein encoded by this gene belongs to the arginine N-methyltransferase family, which catalyze the sequential transfer of methyl group from S-adenosyl-L-methionine to the side chain nitrogens of arginine residues within proteins, to form methylated arginine derivatives and S-adenosyl-L-homocysteine. This protein can catalyze both, the formation of omega-N monomethylarginine and asymmetrical dimethylarginine, with a strong preference for the latter. It specifically mediates the asymmetric dimethylation of Arg2 of histone H3, and the methylated form represents a specific tag for epigenetic transcriptional repression. This protein also forms a complex with, and methylates DNA polymerase beta, resulting in stimulation of polymerase activity by enhancing DNA binding and processivity. [provided by RefSeq, Sep 2011],HRMT1L6,Epigenetic writers and erasers of core Histones,Epigenetic writers and erasers of core Histones_Methylation,Epigenetics & Nuclear Signaling,PRMT6