POGLUT1 anticorps (AA 160-280)

N° du produit ABIN7269673

Cet anticorps Lapin Polyclonal détecte spécifiquement POGLUT1 dans WB et IF. Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour POGLUT1 anticorps (AA 160-280) (ABIN7269673)

Antigène: POGLUT1 (Protein O-Glucosyltransferase 1 (POGLUT1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp POGLUT1 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF)

Détail du produit anti-POGLUT1 anticorps

Épitope: AA 160-280

Fonction: POGLUT1 Rabbit pAb

Séquence: MYPAWTFWEG GPAVWPIYPT GLGRWDLFRE DLVRSAAQWP WKKKNSTAYF RGSRTSPERD PLILLSRKNP KLVDAEYTKN QAWKSMKDTL GKPAAKDVHL VDHCKYKYLF NFRGVAASFR F

Réactivité croisée: Souris, Rat

Attributs du produit: Polyclonal Antibodies

Purification: Affinity purification

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 160-280 of human POGLUT1 (NP_689518.1).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000,IF,1:50 - 1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur POGLUT1

Antigène: POGLUT1 (Protein O-Glucosyltransferase 1 (POGLUT1))

Autre désignation: POGLUT1

Sujet: This gene encodes a protein with both O-glucosyltransferase and O-xylosyltransferase activity which localizes to the lumen of the endoplasmic reticulum. This protein has a carboxy-terminal KTEL motif which is predicted to function as an endoplasmic reticulum retention signal. This gene is an essential regulator of Notch signalling and likely plays a role in cell fate and tissue formation during development. It may also play a role in the pathogenesis of leukemia. Mutations in this gene have been associated with the autosomal dominant genodermatosis Dowling-Degos disease 4. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2014],C3orf9,CLP46,KDELCL1,KTELC1,LGMD2Z,MDS010,MDSRP,Rumi,hCLP46,POGLUT1,Cell Biology & Developmental Biology,POGLUT1

ID gène: 56983

UniProt: Q8NBL1

Pathways: Signalisation Notch