RASD1 anticorps (AA 132-281)

N° du produit ABIN7269879

Détail du produit anti-RASD1 anticorps

Antigène: RASD1 (RAS, Dexamethasone-Induced 1 (RASD1))

Épitope: AA 132-281

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RASD1 est non-conjugé

Application: Western Blotting (WB)

Fonction: RASD1 Rabbit pAb

Séquence: TKENVDVPLV ICGNKGDRDF YREVDQREIE QLVGDDPQRC AYFEISAKKN SSLDQMFRAL FAMAKLPSEM SPDLHRKVSV QYCDVLHKKA LRNKKLLRAG SGGGGGDPGD AFGIVAPFAR RPSVHSDLMY IREKASAGSQ AKDKERCVIS

Réactivité croisée: Humain, Souris

Attributs du produit: Polyclonal Antibodies

Purification: Affinity purification

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 132-281 of human RASD1 (NP_057168.1).

Isotype: IgG

Information d'application

Indications d'application: WB,1:200 - 1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur RASD1

Antigène: RASD1 (RAS, Dexamethasone-Induced 1 (RASD1))

Autre désignation: RASD1 (RASD1 Produits)

Sujet: This gene encodes a member of the Ras superfamily of small GTPases and is induced by dexamethasone. The encoded protein is an activator of G-protein signaling and acts as a direct nucleotide exchange factor for Gi-Go proteins. This protein interacts with the neuronal nitric oxide adaptor protein CAPON, and a nuclear adaptor protein FE65, which interacts with the Alzheimer's disease amyloid precursor protein. This gene may play a role in dexamethasone-induced alterations in cell morphology, growth and cell-extracellular matrix interactions. Epigenetic inactivation of this gene is closely correlated with resistance to dexamethasone in multiple myeloma cells. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.,RASD1,AGS1,DEXRAS1,MGC:26290,Signal Transduction,G protein signaling,Signal Transduction,RASD1

Poids moléculaire: 13kDa/31kDa

ID gène: 51655

UniProt: Q9Y272