Reticulon 3 anticorps (C-Term)

N° du produit ABIN7269929

Détail du produit anti-Reticulon 3 anticorps

Antigène: Reticulon 3 (RTN3)

Épitope: C-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Reticulon 3 est non-conjugé

Application: Western Blotting (WB)

Fonction: RTN3 Rabbit pAb

Séquence: YKSVIQAVQK SEEGHPFKAY LDVDITLSSE AFHNYMNAAM VHINRALKLI IRLFLVEDLV DSLKLAVFMW LMTYVGAVFN GITLLILAEL LIFSVPIVYE KYKTQIDHYV GIARDQTKSI VEKIQAKLPG IAKKKAE

Réactivité croisée: Humain

Attributs du produit: Polyclonal Antibodies

Purification: Affinity purification

Immunogène: A synthetic peptide corresponding to a sequence within amino acids 100 to the C-terminus of human RTN3 (NP_006045.1).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur Reticulon 3

Antigène: Reticulon 3 (RTN3)

Autre désignation: RTN3 (RTN3 Produits)

Synonymes: anticorps ASYIP, anticorps HAP, anticorps NSPL2, anticorps NSPLII, anticorps RTN3-A1, anticorps MGC56439, anticorps zgc:56439, anticorps zgc:77630, anticorps RTN3, anticorps hap, anticorps asyip, anticorps nspl2, anticorps xrtn3, anticorps nsplii, anticorps rtn3-a1, anticorps RTN3w, anticorps rtn3, anticorps XRTN3, anticorps rtn3-a, anticorps rtn3-b, anticorps reticulon 3, anticorps reticulon 3 L homeolog, anticorps reticulon-3, anticorps reticulon 3 S homeolog, anticorps RTN3, anticorps Rtn3, anticorps rtn3, anticorps rnt3, anticorps rtn3.L, anticorps LOC107131155, anticorps rtn3.S

Sujet: This gene belongs to the reticulon family of highly conserved genes that are preferentially expressed in neuroendocrine tissues. This family of proteins interact with, and modulate the activity of beta-amyloid converting enzyme 1 (BACE1), and the production of amyloid-beta. An increase in the expression of any reticulon protein substantially reduces the production of amyloid-beta, suggesting that reticulon proteins are negative modulators of BACE1 in cells. Alternatively spliced transcript variants encoding different isoforms have been found for this gene, and pseudogenes of this gene are located on chromosomes 4 and 12.,RTN3,ASYIP,HAP,NSPL2,NSPLII,RTN3-A1,Signal Transduction,Cell Biology & Developmental Biology,Apoptosis,Endocrine & Metabolism,Mitochondrial metabolism,Mitochondrial markers,RTN3

Poids moléculaire: 23kDa/25kDa/26kDa/27kDa/100kDa/110kDa/112kDa

ID gène: 10313

UniProt: O95197