Retinoblastoma 1 anticorps (pSer780)
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- Antigène Voir toutes Retinoblastoma 1 (RB1) Anticorps
- Retinoblastoma 1 (RB1)
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Épitope
- pSer780
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp Retinoblastoma 1 est non-conjugé
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Application
- Western Blotting (WB), Immunohistochemistry (IHC)
- Fonction
- Phospho-RB-S780 Rabbit mAb
- Réactivité croisée
- Humain, Souris, Rat
- Attributs du produit
- Phosphorylated Antibodies
- Purification
- Affinity purification
- Immunogène
- A phospho synthetic peptide corresponding to residues surrounding S780 of human RB.
- Isotype
- IgG
- Top Product
- Discover our top product RB1 Anticorps primaire
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- Indications d'application
- WB,1:500 - 1:2000,IHC,1:50 - 1:200
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20°C. Avoid freeze / thaw cycles.
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- Antigène
- Retinoblastoma 1 (RB1)
- Autre désignation
- RB1 (RB1 Produits)
- Synonymes
- anticorps OSRC, anticorps RB, anticorps p105-Rb, anticorps pRb, anticorps pp110, anticorps Rb, anticorps Rb-1, anticorps P105-RB, anticorps PP110, anticorps RB11, anticorps zgc:154147, anticorps RB transcriptional corepressor 1, anticorps RB transcriptional corepressor like 1, anticorps retinoblastoma 1, anticorps RB1, anticorps RBL1, anticorps Rb1, anticorps rb1
- Sujet
- The protein encoded by this gene is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma. [provided by RefSeq, Jul 2008],OSRC,PPP1R130,RB,p105-Rb,pRb,pp110,RB1,Rb,Cancer,Cell Biology & Developmental Biology,Cell Cycle,Cell Cycle_Cell cycle inhibitors,DNA Damage & Repair,Epigenetics & Nuclear Signaling,G1/S Checkpoint,Protein phosphorylation,Transcription Factors,Tumor suppressors,RB1
- Poids moléculaire
- 106kDa
- ID gène
- 5925
- UniProt
- P06400
- Pathways
- Cycle Cellulaire, Intracellular Steroid Hormone Receptor Signaling Pathway, Mitotic G1-G1/S Phases, DNA Replication, Maintenance of Protein Location, Synthesis of DNA, Autophagy
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