ARHGAP11B anticorps (AA 218-267)

N° du produit ABIN7269963

Détail du produit anti-ARHGAP11B anticorps

Antigène: ARHGAP11B (rho GTPase Activating Protein 11B (ARHGAP11B))

Épitope: AA 218-267

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ARHGAP11B est non-conjugé

Application: Western Blotting (WB)

Fonction: ARHGAP11B Rabbit pAb

Séquence: EKKGVYQTLS WKRYQPCWVL MVSVLLHHWK ALKKVNMKLL VNIREREDNV

Réactivité croisée: Humain

Attributs du produit: Polyclonal Antibodies

Purification: Affinity purification

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 218-267 of human ARHGAP11B (NP_001034930.1).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur ARHGAP11B

Antigène: ARHGAP11B (rho GTPase Activating Protein 11B (ARHGAP11B))

Autre désignation: ARHGAP11B (ARHGAP11B Produits)

Synonymes: anticorps B'-T, anticorps FAM7B1, anticorps Rho GTPase activating protein 11B, anticorps ARHGAP11B

Sujet: Hominin-specific protein that promotes development and evolutionary expansion of the brain neocortex. Able to promote amplification of basal progenitors in the subventricular zone, producing more neurons during fetal corticogenesis, thereby playing a key role in neocortex expansion. Promotes the proliferation of basal progenitors by inhibiting the mitochondrial permeability transition pore (mPTP: delays the opening of the mPTP via interaction with ADP:ATP translocase, thereby increasing mitochondrial Ca(2+ concentration and inducing glutamine catabolism, which is required for basal progenitor proliferation. Does not possess GTPase activator activity: the absence of GTPase activator activity is required to promote amplification of basal progenitors during neocortex development.,ARHGAP11B,FAM7B1,Signal Transduction,G protein signaling,Signal Transduction,ARHGAP11B

Poids moléculaire: 30kDa

ID gène: 89839

UniProt: Q3KRB8