RBM25 anticorps (AA 614-843)

N° du produit ABIN7270082

Détail du produit anti-RBM25 anticorps

Antigène: RBM25 (RNA Binding Motif Protein 25 (RBM25))

Épitope: AA 614-843

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RBM25 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF)

Fonction: RBM25 Rabbit pAb

Séquence: KPTLRPISSA PSVSSASGNA TPNTPGDESP CGIIIPHENS PDQQQPEEHR PKIGLSLKLG ASNSPGQPNS VKRKKLPVDS VFNKFEDEDS DDVPRKRKLV PLDYGEDDKN ATKGTVNTEE KRKHIKSLIE KIPTAKPELF AYPLDWSIVD SILMERRIRP WINKKIIEYI GEEEATLVDF VCSKVMAHSS PQSILDDVAM VLDEEAEVFI VKMWRLLIYE TEAKKIGLVK

Réactivité croisée: Humain, Souris

Attributs du produit: Polyclonal Antibodies

Purification: Affinity purification

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 614-843 of human RBM25 (NP_067062.1).

Isotype: IgG

Information d'application

Indications d'application: WB,1:200 - 1:2000,IF,1:50 - 1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur RBM25

Antigène: RBM25 (RNA Binding Motif Protein 25 (RBM25))

Autre désignation: RBM25 (RBM25 Produits)

Synonymes: anticorps fi03e10, anticorps zgc:56208, anticorps wu:fi03e10, anticorps si:ch211-105d18.5, anticorps rnpc7, anticorps s164, anticorps NET52, anticorps RED120, anticorps RNPC7, anticorps S164, anticorps Snu71, anticorps fSAP94, anticorps 2600011C06Rik, anticorps 2610015J01Rik, anticorps A130095G20Rik, anticorps AI159652, anticorps AL023075, anticorps AU043498, anticorps RNA binding motif protein 25b, anticorps RNA binding motif protein 25, anticorps RNA binding motif protein 25 S homeolog, anticorps putative rna binding motif protein 25, anticorps rbm25b, anticorps Rbm25, anticorps rbm25.S, anticorps rbm25, anticorps RBM25, anticorps Smp_078610

Sujet: RNA-binding protein that acts as a regulator of alternative pre-mRNA splicing. Involved in apoptotic cell death through the regulation of the apoptotic factor BCL2L1 isoform expression. Modulates the ratio of proapoptotic BCL2L1 isoform S to antiapoptotic BCL2L1 isoform L mRNA expression. When overexpressed, stimulates proapoptotic BCL2L1 isoform S 5'-splice site (5'-ss selection, whereas its depletion caused the accumulation of antiapoptotic BCL2L1 isoform L. Promotes BCL2L1 isoform S 5'-ss usage through the 5'-CGGGCA-3' RNA sequence. Its association with LUC7L3 promotes U1 snRNP binding to a weak 5' ss in a 5'-CGGGCA-3'-dependent manner. Binds to the exonic splicing enhancer 5'-CGGGCA-3' RNA sequence located within exon 2 of the BCL2L1 pre-mRNA. Also involved in the generation of an abnormal and truncated splice form of SCN5A in heart failure.,RBM25,NET52,RED120,RNPC7,S164,Snu71,fSAP94,Epigenetics & Nuclear Signaling,RNA Binding,RBM25

Poids moléculaire: 17kDa/32kDa/33kDa/100kDa

ID gène: 58517

UniProt: P49756