Selenoprotein S anticorps (AA 50-150)

N° du produit ABIN7270197

Détail du produit anti-Selenoprotein S anticorps

Antigène: Selenoprotein S (SELS)

Épitope: AA 50-150

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Selenoprotein S est non-conjugé

Application: Western Blotting (WB)

Fonction: VIMP Rabbit pAb

Séquence: KLSARLRALR QRQLDRAAAA VEPDVVVKRQ EALAAARLKM QEELNAQVEK HKEKLKQLEE EKRRQKIEMW DSMQEGKSYK GNAKKPQEED SPGPSTSSVL K

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Polyclonal Antibodies

Purification: Affinity purification

Immunogène: A synthetic peptide corresponding to a sequence within amino acids 50-150 of human VIMP (NP_982298.2).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur Selenoprotein S

Antigène: Selenoprotein S (SELS)

Autre désignation: SELENOS (SELS Produits)

Synonymes: anticorps ADO15, anticorps SBBI8, anticorps SELS, anticorps SEPS1, anticorps 1500011E07Rik, anticorps C78786, anticorps H-4, anticorps H-47, anticorps H4, anticorps H47, anticorps Sels, anticorps sg2, anticorps selenoprotein S, anticorps SELENOS, anticorps Selenos

Sujet: This gene encodes a transmembrane protein that is localized in the endoplasmic reticulum (ER). It is involved in the degradation process of misfolded proteins in the ER, and may also have a role in inflammation control. This protein is a selenoprotein, containing the rare amino acid selenocysteine (Sec). Sec is encoded by the UGA codon, which normally signals translation termination. The 3' UTRs of selenoprotein mRNAs contain a conserved stem-loop structure, designated the Sec insertion sequence (SECIS) element, that is necessary for the recognition of UGA as a Sec codon, rather than as a stop signal. Two additional phylogenetically conserved stem-loop structures (Stem-loop 1 and Stem-loop 2) in the 3' UTR have been shown to function as modulators of Sec insertion in this protein (PMID:23614019). An alternatively spliced transcript variant, lacking the SECIS element and encoding a non-Sec containing shorter isoform, has been described for this gene.,SELENOS,AD-015,ADO15,SBBI8,SELS,SEPS1,VIMP,Signal Transduction,Immunology & Inflammation,Cell Intrinsic Innate Immunity Signaling Pathway,SELENOS

Poids moléculaire: 21kDa

ID gène: 55829

UniProt: Q9BQE4

Pathways: Cellular Response to Molecule of Bacterial Origin, ER-Nucleus Signaling, Regulation of Carbohydrate Metabolic Process, Cell RedoxHomeostasis, Negative Regulation of intrinsic apoptotic Signaling, SARS-CoV-2 Protein Interactome