SESN1 anticorps
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- Antigène Voir toutes SESN1 Anticorps
- SESN1 (Sestrin 1 (SESN1))
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp SESN1 est non-conjugé
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Application
- Western Blotting (WB), Immunohistochemistry (IHC)
- Fonction
- sestrin 1 Rabbit mAb
- Réactivité croisée
- Humain, Souris, Rat
- Attributs du produit
- Monoclonal Antibodies
- Purification
- Affinity purification
- Immunogène
- A synthesized peptide derived from human sestrin 1
- Isotype
- IgG
- Top Product
- Discover our top product SESN1 Anticorps primaire
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- Indications d'application
- WB,1:500 - 1:2000,IHC,1:50 - 1:200
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20°C. Avoid freeze / thaw cycles.
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- Antigène
- SESN1 (Sestrin 1 (SESN1))
- Autre désignation
- SESN1 (SESN1 Produits)
- Sujet
- This gene encodes a member of the sestrin family. Sestrins are induced by the p53 tumor suppressor protein and play a role in the cellular response to DNA damage and oxidative stress. The encoded protein mediates p53 inhibition of cell growth by activating AMP-activated protein kinase, which results in the inhibition of the mammalian target of rapamycin protein. The encoded protein also plays a critical role in antioxidant defense by regenerating overoxidized peroxiredoxins, and the expression of this gene is a potential marker for exposure to radiation. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2010],PA26, SEST1,AMPK Signaling Pathway,Cell Biology & Developmental Biology,Endocrine & Metabolism,Endocrine and metabolic diseases,Endocrine and metabolic diseases_Obesity,SESN1
- Poids moléculaire
- 70kDa
- ID gène
- 27244
- UniProt
- Q9Y6P5
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