SETD4 anticorps (AA 210-300)

N° du produit ABIN7270264

Détail du produit anti-SETD4 anticorps

Antigène: SETD4 (SET Domain Containing 4 (SETD4))

Épitope: AA 210-300

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SETD4 est non-conjugé

Application: Western Blotting (WB)

Fonction: SETD4 Rabbit pAb

Séquence: YLRPRQRECL SAEPDTCALA PYLDLLNHSP HVQVKAAFNE ETHSYEIRTT SRWRKHEEVF ICYGPHDNQR LFLEYGFVSV HNPHACVYVS R

Réactivité croisée: Humain, Souris

Attributs du produit: Polyclonal Antibodies

Purification: Affinity purification

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 210-300 of human SETD4 (NP_001007260).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur SETD4

Antigène: SETD4 (SET Domain Containing 4 (SETD4))

Autre désignation: SETD4 (SETD4 Produits)

Synonymes: anticorps MGC53706, anticorps dZ63M10.4, anticorps zgc:112252, anticorps C21orf18, anticorps C21orf27, anticorps AY037804, anticorps ORF21, anticorps Rda279, anticorps SET domain containing 4 L homeolog, anticorps SET domain containing 4, anticorps setd4.L, anticorps SETD4, anticorps setd4, anticorps Setd4

Sujet: Histone-lysine N-methyltransferase that acts as a regulator of cell proliferation, cell differentiation and inflammatory response. Regulates the inflammatory response by mediating mono- and dimethylation of 'Lys-4' of histone H3 (H3K4me1 and H3K4me2, respectively, leading to activate the transcription of proinflammatory cytokines IL6 and TNF-alpha (By similarity. Also involved in the regulation of stem cell quiescence by catalyzing the trimethylation of 'Lys-20' of histone H4 (H4K20me3, thereby promoting heterochromatin formation. Involved in proliferation, migration, paracrine and myogenic differentiation of bone marrow mesenchymal stem cells (BMSCs (By similarity.,C21orf18,C21orf27,SETD4,Epigenetics & Nuclear Signaling,SETD4

ID gène: 54093

UniProt: Q9NVD3