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SYNGAP1 anticorps

SYNGAP1 Reactivité: Humain WB Hôte: Lapin Monoclonal unconjugated
N° du produit ABIN7270663
  • Antigène Voir toutes SYNGAP1 Anticorps
    SYNGAP1 (Synaptic Ras GTPase Activating Protein 1 (SYNGAP1))
    Reactivité
    • 20
    • 16
    • 14
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 19
    • 2
    Lapin
    Clonalité
    • 19
    • 2
    Monoclonal
    Conjugué
    • 11
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp SYNGAP1 est non-conjugé
    Application
    • 10
    • 8
    • 5
    • 2
    • 2
    Western Blotting (WB)
    Fonction
    SynGAP Rabbit mAb
     Réactivité croisée
    Humain, Souris, Rat
    Attributs du produit
    Monoclonal Antibodies
    Purification
    Affinity purification
    Immunogène
    A synthesized peptide derived from human SynGAP
    Isotype
    IgG
    Top Product
    Discover our top product SYNGAP1 Anticorps primaire
  • Indications d'application
    WB,1:500 - 1:2000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C. Avoid freeze / thaw cycles.
  • Antigène
    SYNGAP1 (Synaptic Ras GTPase Activating Protein 1 (SYNGAP1))
    Autre désignation
    SYNGAP1 (SYNGAP1 Produits)
    Synonymes
    anticorps SYNGAP1, anticorps Syngap, anticorps MRD5, anticorps RASA1, anticorps RASA5, anticorps SYNGAP, anticorps Gm1963, anticorps synaptic Ras GTPase activating protein 1, anticorps zinc finger and BTB domain containing 9, anticorps synaptic Ras GTPase activating protein 1 homolog (rat), anticorps SYNGAP1, anticorps ZBTB9, anticorps syngap1, anticorps Syngap1
    Sujet
    This gene encodes a Ras GTPase activating protein that is a member of the N-methyl-D-aspartate receptor complex. The N-terminal domain of the protein contains a Ras-GAP domain, a pleckstrin homology domain, and a C2 domain that may be involved in binding of calcium and phospholipids. The C-terminal domain consists of a ten histidine repeat region, serine and tyrosine phosphorylation sites, and a T/SXV motif required for postsynaptic scaffold protein interaction. The encoded protein negatively regulates Ras, Rap and alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor trafficking to the postsynaptic membrane to regulate synaptic plasticity and neuronal homeostasis. Allelic variants of this gene are associated with intellectual disability and autism spectrum disorder. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2016],MRD5, RASA1, RASA5, SYNGAP,Cell Type Marker,Cell Type Marker_Neuron marker,Cell Type Marker_Synapse marker,G protein signaling,G protein signaling_G-Protein-Coupled Receptors Signaling to MAPK/Erk,Neuroscience,Signal Transduction,SYNGAP1
    Poids moléculaire
    147kDa
    ID gène
    8831
    UniProt
    Q96PV0
    Pathways
    Regulation of long-term Neuronal Synaptic Plasticity
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