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TTC3 anticorps (AA 1400-1700)

TTC3 Reactivité: Humain WB Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN7270791
  • Antigène Voir toutes TTC3 Anticorps
    TTC3 (Tetratricopeptide Repeat Domain 3 (TTC3))
    Épitope
    • 3
    • 2
    • 1
    AA 1400-1700
    Reactivité
    • 4
    • 4
    • 3
    Humain
    Hôte
    • 5
    • 2
    Lapin
    Clonalité
    • 6
    • 1
    Polyclonal
    Conjugué
    • 5
    • 1
    • 1
    Cet anticorp TTC3 est non-conjugé
    Application
    • 4
    • 3
    • 2
    • 1
    Western Blotting (WB)
    Fonction
    TTC3 Rabbit pAb
    Séquence
    IASETQILEG SLGISVKSHC STGDAHTVLS ESNRNDEHCG NSNNKCEVIP ESTSAVTNIP HVQMVAIQVS WNIIHQEVNT EPYNPFEERQ GEISRIEKEH QVLQDQLQEV YENYEQIKLK GLEETRDLEE KLKRHLEENK ISKTELDWFL QDLEREIKKW QQEKKEIQER LKSLKKKIKK VSNASEMYTQ KNDGKEKEHE LHLDQSLEIS NTLTNEKMKI EEYIKKGKED YEESHQRAVA AEVSVLENWK ESEVYKLQIM ESQAEAFLKK LGLISRDPAA YPDMESDIRS WELFLSNVTK E
     Réactivité croisée
    Humain, Souris, Rat
    Attributs du produit
    Polyclonal Antibodies
    Purification
    Affinity purification
    Immunogène
    Recombinant fusion protein containing a sequence corresponding to amino acids 1400-1700 of human TTC3 (NP_003307.3).
    Isotype
    IgG
    Top Product
    Discover our top product TTC3 Anticorps primaire
  • Indications d'application
    WB,1:500 - 1:2000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C. Avoid freeze / thaw cycles.
  • Antigène
    TTC3 (Tetratricopeptide Repeat Domain 3 (TTC3))
    Autre désignation
    TTC3 (TTC3 Produits)
    Synonymes
    anticorps DCRR1, anticorps RNF105, anticorps TPRDIII, anticorps 2610202A04Rik, anticorps AA409221, anticorps D16Ium21, anticorps D16Ium21e, anticorps TPRD, anticorps mKIAA4119, anticorps TTC3, anticorps tetratricopeptide repeat domain 3, anticorps E3 ubiquitin-protein ligase TTC3, anticorps TTC3, anticorps Ttc3, anticorps LOC100562480
    Sujet
    E3 ubiquitin-protein ligase which catalyzes the formation of 'Lys-48'-polyubiquitin chains. Mediates the ubiquitination and subsequent degradation of phosphorylated Akt (AKT1, AKT2 and AKT3 in the nucleus. Acts as a terminal regulator of Akt signaling after activation, its phosphorylation by Akt, which is a prerequisite for ubiquitin ligase activity, suggests the existence of a regulation mechanism required to control Akt levels after activation. Positively regulates TGFB1-induced epithelial-mesenchymal transition and myofibroblast differentiation by mediating the ubiquitination and subsequent degradation of SMURF2. Regulates neuronal differentiation by regulating actin remodeling and Golgi organization via a signaling cascade involving RHOA, CIT and ROCK. Inhibits cell proliferation.,TTC3,DCRR1,RNF105,TPRDIII,Signal Transduction,G protein signaling,Signal Transduction,Cell Biology & Developmental Biology,Ubiquitin,Neuroscience,TTC3
    Poids moléculaire
    194kDa/203kDa/229kDa
    ID gène
    7267
    UniProt
    P53804
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