TTC3 anticorps (AA 1400-1700)
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- Antigène Voir toutes TTC3 Anticorps
- TTC3 (Tetratricopeptide Repeat Domain 3 (TTC3))
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Épitope
- AA 1400-1700
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp TTC3 est non-conjugé
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Application
- Western Blotting (WB)
- Fonction
- TTC3 Rabbit pAb
- Séquence
- IASETQILEG SLGISVKSHC STGDAHTVLS ESNRNDEHCG NSNNKCEVIP ESTSAVTNIP HVQMVAIQVS WNIIHQEVNT EPYNPFEERQ GEISRIEKEH QVLQDQLQEV YENYEQIKLK GLEETRDLEE KLKRHLEENK ISKTELDWFL QDLEREIKKW QQEKKEIQER LKSLKKKIKK VSNASEMYTQ KNDGKEKEHE LHLDQSLEIS NTLTNEKMKI EEYIKKGKED YEESHQRAVA AEVSVLENWK ESEVYKLQIM ESQAEAFLKK LGLISRDPAA YPDMESDIRS WELFLSNVTK E
- Réactivité croisée
- Humain, Souris, Rat
- Attributs du produit
- Polyclonal Antibodies
- Purification
- Affinity purification
- Immunogène
- Recombinant fusion protein containing a sequence corresponding to amino acids 1400-1700 of human TTC3 (NP_003307.3).
- Isotype
- IgG
- Top Product
- Discover our top product TTC3 Anticorps primaire
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- Indications d'application
- WB,1:500 - 1:2000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20°C. Avoid freeze / thaw cycles.
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- Antigène
- TTC3 (Tetratricopeptide Repeat Domain 3 (TTC3))
- Autre désignation
- TTC3 (TTC3 Produits)
- Synonymes
- anticorps DCRR1, anticorps RNF105, anticorps TPRDIII, anticorps 2610202A04Rik, anticorps AA409221, anticorps D16Ium21, anticorps D16Ium21e, anticorps TPRD, anticorps mKIAA4119, anticorps TTC3, anticorps tetratricopeptide repeat domain 3, anticorps E3 ubiquitin-protein ligase TTC3, anticorps TTC3, anticorps Ttc3, anticorps LOC100562480
- Sujet
- E3 ubiquitin-protein ligase which catalyzes the formation of 'Lys-48'-polyubiquitin chains. Mediates the ubiquitination and subsequent degradation of phosphorylated Akt (AKT1, AKT2 and AKT3 in the nucleus. Acts as a terminal regulator of Akt signaling after activation, its phosphorylation by Akt, which is a prerequisite for ubiquitin ligase activity, suggests the existence of a regulation mechanism required to control Akt levels after activation. Positively regulates TGFB1-induced epithelial-mesenchymal transition and myofibroblast differentiation by mediating the ubiquitination and subsequent degradation of SMURF2. Regulates neuronal differentiation by regulating actin remodeling and Golgi organization via a signaling cascade involving RHOA, CIT and ROCK. Inhibits cell proliferation.,TTC3,DCRR1,RNF105,TPRDIII,Signal Transduction,G protein signaling,Signal Transduction,Cell Biology & Developmental Biology,Ubiquitin,Neuroscience,TTC3
- Poids moléculaire
- 194kDa/203kDa/229kDa
- ID gène
- 7267
- UniProt
- P53804
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