TOP1MT anticorps (AA 470-550)

N° du produit ABIN7270851

Détail du produit anti-TOP1MT anticorps

Antigène: TOP1MT (Topoisomerase (DNA) I, Mitochondrial (TOP1MT))

Épitope: AA 470-550

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TOP1MT est non-conjugé

Application: Immunohistochemistry (IHC), Western Blotting (WB)

Fonction: TOP1MT Rabbit pAb

Séquence: RATPSTFEKS MQNLQTKIQA KKEQVAEARA ELRRARAEHK AQGDGKSRSV LEKKRRLLEK LQEQLAQLSV QATDKEENKQ V

Réactivité croisée: Humain, Rat

Attributs du produit: Polyclonal Antibodies

Purification: Affinity purification

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 470-550 of human TOP1MT (NP_443195.1).

Isotype: IgG

Information d'application

Indications d'application: WB,1:200 - 1:2000,IHC,1:50 - 1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur TOP1MT

Antigène: TOP1MT (Topoisomerase (DNA) I, Mitochondrial (TOP1MT))

Autre désignation: TOP1MT (TOP1MT Produits)

Synonymes: anticorps 2900052H09Rik, anticorps TOP1, anticorps topoisomerase (DNA) I, mitochondrial, anticorps DNA topoisomerase 1, mitochondrial, anticorps DNA topoisomerase I mitochondrial, anticorps TOP1MT, anticorps Top1mt

Sujet: This gene encodes a mitochondrial DNA topoisomerase that plays a role in the modification of DNA topology. The encoded protein is a type IB topoisomerase and catalyzes the transient breaking and rejoining of DNA to relieve tension and DNA supercoiling generated in the mitochondrial genome during replication and transcription. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.,TOP1MT,Epigenetics & Nuclear Signaling,Cancer,Drug resistance,Topoisomerases,TOP1MT

Poids moléculaire: 58kDa/69kDa

ID gène: 116447

UniProt: Q969P6