TPSB2 anticorps (AA 1-275)

N° du produit ABIN7271018

Détail du produit anti-TPSB2 anticorps

Antigène: TPSB2 (Tryptase beta 2 (TPSB2))

Épitope: AA 1-275

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TPSB2 est non-conjugé

Application: Western Blotting (WB)

Fonction: Mast Cell Tryptase (TPSB2) Rabbit pAb

Séquence: MLNLLLLALP VLASRAYAAP APGQALQRVG IVGGQEAPRS KWPWQVSLRV RDRYWMHFCG GSLIHPQWVL TAAHCVGPDV KDLAALRVQL REQHLYYQDQ LLPVSRIIVH PQFYTAQIGA DIALLELEEP VNVSSHVHTV TLPPASETFP PGMPCWVTGW GDVDNDERLP PPFPLKQVKV PIMENHICDA KYHLGAYTGD DVRIVRDDML CAGNTRRDSC QGDSGGPLVC KVNGTWLQAG VVSWGEGCAQ PNRPGIYTRV TYYLDWIHHY VPKKP

Réactivité croisée: Humain, Rat

Attributs du produit: Polyclonal Antibodies

Purification: Affinity purification

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 1-275 of human Mast Cell Tryptase (Mast Cell Tryptase (TPSB2)) (NP_077078.5).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur TPSB2

Antigène: TPSB2 (Tryptase beta 2 (TPSB2))

Autre désignation: TPSB2 (TPSB2 Produits)

Synonymes: anticorps TPS2, anticorps tryptaseB, anticorps tryptaseC, anticorps Mcpt6, anticorps tryptase beta 2 (gene/pseudogene), anticorps tryptase beta 2, anticorps TPSB2, anticorps Tpsb2

Sujet: Tryptases comprise a family of trypsin-like serine proteases, the peptidase family S1. Tryptases are enzymatically active only as heparin-stabilized tetramers, and they are resistant to all known endogenous proteinase inhibitors. Several tryptase genes are clustered on chromosome 16p13.3. These genes are characterized by several distinct features. They have a highly conserved 3' UTR and contain tandem repeat sequences at the 5' flank and 3' UTR which are thought to play a role in regulation of the mRNA stability. These genes have an intron immediately upstream of the initiator Met codon, which separates the site of transcription initiation from protein coding sequence. This feature is characteristic of tryptases but is unusual in other genes. The alleles of this gene exhibit an unusual amount of sequence variation, such that the alleles were once thought to represent two separate genes, beta II and beta III. Beta tryptases appear to be the main isoenzymes expressed in mast cells, whereas in basophils, alpha-tryptases predominate. Tryptases have been implicated as mediators in the pathogenesis of asthma and other allergic and inflammatory disorders.,TPSB2,TPS2,tryptaseB,tryptaseC,Cell Biology & Developmental Biology,Ubiquitin,Immunology & Inflammation,Cell Intrinsic Innate Immunity Signaling Pathway,TPSB2

Poids moléculaire: 30kDa

ID gène: 64499

UniProt: P20231