TNFSF9 anticorps

N° du produit ABIN7271060

Détail du produit anti-TNFSF9 anticorps

Antigène: TNFSF9 (Tumor Necrosis Factor (Ligand) Superfamily, Member 9 (TNFSF9))

Reactivité: Humain

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp TNFSF9 est non-conjugé

Application: Western Blotting (WB)

Fonction: 4-1BBL/CD137L Rabbit mAb

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Monoclonal Antibodies

Purification: Affinity purification

Immunogène: A synthesized peptide derived from human 4-1BBL/CD137L

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur TNFSF9

Antigène: TNFSF9 (Tumor Necrosis Factor (Ligand) Superfamily, Member 9 (TNFSF9))

Autre désignation: TNFSF9 (TNFSF9 Produits)

Synonymes: anticorps TNFSF9, anticorps 4-1BB-L, anticorps 4-1BBL, anticorps AI848817, anticorps Cd137l, anticorps Ly63l, anticorps CD137L, anticorps TNF superfamily member 9, anticorps tumor necrosis factor (ligand) superfamily, member 9, anticorps Tnfsf9, anticorps LOC476729, anticorps TNFSF9

Sujet: The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This transmembrane cytokine is a bidirectional signal transducer that acts as a ligand for TNFRSF9/4-1BB, which is a costimulatory receptor molecule in T lymphocytes. This cytokine and its receptor are involved in the antigen presentation process and in the generation of cytotoxic T cells. The receptor TNFRSF9/4-1BB is absent from resting T lymphocytes but rapidly expressed upon antigenic stimulation. The ligand encoded by this gene, TNFSF9/4-1BBL, has been shown to reactivate anergic T lymphocytes in addition to promoting T lymphocyte proliferation. This cytokine has also been shown to be required for the optimal CD8 responses in CD8 T cells. This cytokine is expressed in carcinoma cell lines, and is thought to be involved in T cell-tumor cell interaction.[provided by RefSeq, Oct 2008],4-1BB-L, CD137L, TNLG5A,Apoptosis,Cancer,Cell Biology & Developmental Biology,Cell Intrinsic Innate Immunity Signaling Pathway,Cytokines,Cytokines_TNF,Growth factors,Growth factors_TNF,Immunology & Inflammation,TNFSF9

Poids moléculaire: 25-32kDa

ID gène: 8744

UniProt: P41273

Pathways: Activated T Cell Proliferation, Cancer Immune Checkpoints