UIMC1 anticorps (AA 449-719)

N° du produit ABIN7271136

Détail du produit anti-UIMC1 anticorps

Antigène: UIMC1 (Ubiquitin Interaction Motif Containing 1 (UIMC1))

Épitope: AA 449-719

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp UIMC1 est non-conjugé

Application: Western Blotting (WB)

Fonction: UIMC1 Rabbit pAb

Séquence: QLSSSETFDL EREVSPGSRD ILDGVRIIMA DKEVGNKEDA EKEVAISTFS SSNQVSCPLC DQCFPPTKIE RHAMYCNGLM EEDTVLTRRQ KEAKTKSDSG TAAQTSLDID KNEKCYLCKS LVPFREYQCH VDSCLQLAKA DQGDGPEGSG RACSTVEGKW QQRLKNPKEK GHSEGRLLSF LEQSEHKTSD ADIKSSETGA FRVPSPGMEE AGCSREMQSS FTRRDLNESP VKSFVSISEA TDCLVDFKKQ VTVQPGSRTR TKAGRGRRRK F

Réactivité croisée: Humain, Souris

Attributs du produit: Polyclonal Antibodies

Purification: Affinity purification

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 449-719 of human UIMC1 (NP_057374.3).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur UIMC1

Antigène: UIMC1 (Ubiquitin Interaction Motif Containing 1 (UIMC1))

Autre désignation: UIMC1 (UIMC1 Produits)

Synonymes: anticorps UIMC1, anticorps RAP80, anticorps X2HRIP110, anticorps 9430016E08Rik, anticorps D330018D10Rik, anticorps D630032M02Rik, anticorps RIP110, anticorps Rxrip110, anticorps RGD1307009, anticorps ubiquitin interaction motif containing 1, anticorps UIMC1, anticorps Uimc1

Sujet: This gene encodes a nuclear protein that interacts with Brca1 (breast cancer 1) in a complex to recognize and repair DNA lesions. This protein binds ubiquitinated lysine 63 of histone H2A and H2AX. This protein may also function as a repressor of transcription. Alternative splicing results in multiple transcript variants.,UIMC1,RAP80,X2HRIP110,Epigenetics & Nuclear Signaling,DNA Damage & Repair,Nuclear Receptor Signaling,Cell Biology & Developmental Biology,Ubiquitin,UIMC1

Poids moléculaire: 17kDa/38kDa/61kDa/70kDa/79kDa

ID gène: 51720

UniProt: Q96RL1

Pathways: Réparation de l'ADN, Nuclear Hormone Receptor Binding, Positive Regulation of Response to DNA Damage Stimulus