USP37 anticorps (AA 150-250)

N° du produit ABIN7271158

Détail du produit anti-USP37 anticorps

Antigène: USP37 (Ubiquitin Specific Peptidase 37 (USP37))

Épitope: AA 150-250

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp USP37 est non-conjugé

Application: Western Blotting (WB)

Fonction: USP37 Rabbit pAb

Séquence: SLETKDDIPF RKVLGNPGRG SIKTVAGSGI ARTIPSLTST STPLRSGLLE NRTEKRKRMI STGSELNEDY PKENDSSSNN KAMTDPSRKY LTSSREKQLS L

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Polyclonal Antibodies

Purification: Affinity purification

Immunogène: A synthetic peptide corresponding to a sequence within amino acids 150-250 of human USP37 (NP_065986.2).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur USP37

Antigène: USP37 (Ubiquitin Specific Peptidase 37 (USP37))

Autre désignation: USP37 (USP37 Produits)

Synonymes: anticorps 4932415L06Rik, anticorps C330008N13Rik, anticorps wu:fi15b04, anticorps wu:fi38d03, anticorps zgc:152882, anticorps zgc:153999, anticorps ubiquitin specific peptidase 37, anticorps USP37, anticorps usp37, anticorps Usp37

Sujet: Deubiquitinase that antagonizes the anaphase-promoting complex (APC/C during G1/S transition by mediating deubiquitination of cyclin-A (CCNA1 and CCNA2, thereby promoting S phase entry. Specifically mediates deubiquitination of 'Lys-11'-linked polyubiquitin chains, a specific ubiquitin-linkage type mediated by the APC/C complex. Also mediates deubiquitination of 'Lys-48'-linked polyubiquitin chains in vitro. Phosphorylation at Ser-628 during G1/S phase maximizes the deubiquitinase activity, leading to prevent degradation of cyclin-A (CCNA1 and CCNA2. Plays an important role in the regulation of DNA replication by stabilizing the licensing factor CDT1.,USP37,Epigenetics & Nuclear Signaling,Cell Biology & Developmental Biology,Ubiquitin,USP37

Poids moléculaire: 99kDa/110kDa

ID gène: 57695

UniProt: Q86T82