UGT1A10 anticorps (AA 50-150)

N° du produit ABIN7271191

Détail du produit anti-UGT1A10 anticorps

Antigène: UGT1A10 (UDP Glucuronosyltransferase 1 Family, Polypeptide A10 (UGT1A10))

Épitope: AA 50-150

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp UGT1A10 est non-conjugé

Application: Western Blotting (WB)

Fonction: UGT1A10 Rabbit pAb

Séquence: LRGHEVVVVM PEVSWQLERS LNCTVKTYST SYTLEDQNRE FMVFAHAQWK AQAQSIFSLL MSSSSGFLDL FFSHCRSLFN DRKLVEYLKE SSFDAVFLDP F

Réactivité croisée: Humain

Attributs du produit: Polyclonal Antibodies

Purification: Affinity purification

Immunogène: A synthetic peptide corresponding to a sequence within amino acids 50-150 of human UGT1A10 (NP_061948.1).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur UGT1A10

Antigène: UGT1A10 (UDP Glucuronosyltransferase 1 Family, Polypeptide A10 (UGT1A10))

Autre désignation: UGT1A10 (UGT1A10 Produits)

Synonymes: anticorps UDPGT, anticorps UGT-1J, anticorps UGT1-10, anticorps UGT1.10, anticorps UGT1J, anticorps A13, anticorps Ugt1a13, anticorps UDP glucuronosyltransferase family 1 member A10, anticorps UDP glycosyltransferase 1 family, polypeptide A10, anticorps UGT1A10, anticorps Ugt1a10

Sujet: This gene encodes a UDP-glucuronosyltransferase, an enzyme of the glucuronidation pathway that transforms small lipophilic molecules, such as steroids, bilirubin, hormones, and drugs, into water-soluble, excretable metabolites. This gene is part of a complex locus that encodes several UDP-glucuronosyltransferases. The locus includes thirteen unique alternate first exons followed by four common exons. Four of the alternate first exons are considered pseudogenes. Each of the remaining nine 5' exons may be spliced to the four common exons, resulting in nine proteins with different N-termini and identical C-termini. Each first exon encodes the substrate binding site, and is regulated by its own promoter. The enzyme encoded by this gene has glucuronidase activity on mycophenolic acid, coumarins, and quinolines.,UGT1A10;UDPGT;UGT-1J;UGT1-10;UGT1.10;UGT1J,Signal Transduction,Endocrine & Metabolism,Drug metabolism,UGT1A10

Poids moléculaire: 49kDa/59kDa

ID gène: 54575

UniProt: Q9HAW8

Pathways: Steroid Hormone Biosynthesis, Regulation of Lipid Metabolism by PPARalpha