ULK3 anticorps
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- Antigène Voir toutes ULK3 Anticorps
- ULK3 (Unc-51-Like Kinase 3 (ULK3))
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp ULK3 est non-conjugé
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Application
- Western Blotting (WB), Immunofluorescence (IF)
- Fonction
- ULK3 Rabbit mAb
- Réactivité croisée
- Humain, Souris, Rat
- Attributs du produit
- Monoclonal Antibodies
- Purification
- Affinity purification
- Immunogène
- A synthesized peptide derived from human ULK3
- Isotype
- IgG
- Top Product
- Discover our top product ULK3 Anticorps primaire
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- Indications d'application
- WB,1:500 - 1:2000,IF,1:50 - 1:200
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20°C. Avoid freeze / thaw cycles.
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- Antigène
- ULK3 (Unc-51-Like Kinase 3 (ULK3))
- Autre désignation
- ULK3 (ULK3 Produits)
- Synonymes
- anticorps zgc:162196, anticorps 1200015E14Rik, anticorps unc-51 like kinase 3, anticorps unc-51 like kinase 3 L homeolog, anticorps unc-51-like kinase 3, anticorps ULK3, anticorps ulk3, anticorps Ulk3, anticorps ulk3.L
- Sujet
- Serine/threonine protein kinase that acts as a regulator of Sonic hedgehog (SHH signaling and autophagy. Acts as a negative regulator of SHH signaling in the absence of SHH ligand: interacts with SUFU, thereby inactivating the protein kinase activity and preventing phosphorylation of GLI proteins (GLI1, GLI2 and/or GLI3. Positively regulates SHH signaling in the presence of SHH: dissociates from SUFU, autophosphorylates and mediates phosphorylation of GLI2, activating it and promoting its nuclear translocation. Phosphorylates in vitro GLI2, as well as GLI1 and GLI3, although less efficiently. Also acts as a regulator of autophagy: following cellular senescence, able to induce autophagy.,Autophagy,Cell Biology & Developmental Biology,Endocrine & Metabolism,Kinase,Mitochondrial metabolism,Signal Transduction,ULK3
- Poids moléculaire
- 53kDa
- ID gène
- 25989
- UniProt
- Q6PHR2
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