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ULK3 anticorps

ULK3 Reactivité: Humain WB, IF Hôte: Lapin Monoclonal unconjugated
N° du produit ABIN7271222
  • Antigène Voir toutes ULK3 Anticorps
    ULK3 (Unc-51-Like Kinase 3 (ULK3))
    Reactivité
    • 53
    • 46
    • 16
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    Humain
    Hôte
    • 61
    • 6
    • 2
    Lapin
    Clonalité
    • 65
    • 4
    Monoclonal
    Conjugué
    • 30
    • 6
    • 6
    • 6
    • 6
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp ULK3 est non-conjugé
    Application
    • 60
    • 40
    • 10
    • 9
    • 8
    • 6
    • 3
    Western Blotting (WB), Immunofluorescence (IF)
    Fonction
    ULK3 Rabbit mAb
     Réactivité croisée
    Humain, Souris, Rat
    Attributs du produit
    Monoclonal Antibodies
    Purification
    Affinity purification
    Immunogène
    A synthesized peptide derived from human ULK3
    Isotype
    IgG
    Top Product
    Discover our top product ULK3 Anticorps primaire
  • Indications d'application
    WB,1:500 - 1:2000,IF,1:50 - 1:200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C. Avoid freeze / thaw cycles.
  • Antigène
    ULK3 (Unc-51-Like Kinase 3 (ULK3))
    Autre désignation
    ULK3 (ULK3 Produits)
    Synonymes
    anticorps zgc:162196, anticorps 1200015E14Rik, anticorps unc-51 like kinase 3, anticorps unc-51 like kinase 3 L homeolog, anticorps unc-51-like kinase 3, anticorps ULK3, anticorps ulk3, anticorps Ulk3, anticorps ulk3.L
    Sujet
    Serine/threonine protein kinase that acts as a regulator of Sonic hedgehog (SHH signaling and autophagy. Acts as a negative regulator of SHH signaling in the absence of SHH ligand: interacts with SUFU, thereby inactivating the protein kinase activity and preventing phosphorylation of GLI proteins (GLI1, GLI2 and/or GLI3. Positively regulates SHH signaling in the presence of SHH: dissociates from SUFU, autophosphorylates and mediates phosphorylation of GLI2, activating it and promoting its nuclear translocation. Phosphorylates in vitro GLI2, as well as GLI1 and GLI3, although less efficiently. Also acts as a regulator of autophagy: following cellular senescence, able to induce autophagy.,Autophagy,Cell Biology & Developmental Biology,Endocrine & Metabolism,Kinase,Mitochondrial metabolism,Signal Transduction,ULK3
    Poids moléculaire
    53kDa
    ID gène
    25989
    UniProt
    Q6PHR2
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