anticorps wu:fi20f07, anticorps wu:fi22c06, anticorps LRPAP1, anticorps DKFZp459I2430, anticorps A2MRAP, anticorps A2RAP, anticorps HBP44, anticorps MRAP, anticorps RAP, anticorps AA617339, anticorps AI790446, anticorps AU042172, anticorps C77774, anticorps alpha-2-macroglobulin receptor-associated protein-like, anticorps low density lipoprotein receptor-related protein associated protein 1, anticorps LDL receptor related protein associated protein 1, anticorps LDL receptor related protein associated protein 1 L homeolog, anticorps LOC100231803, anticorps lrpap1, anticorps LRPAP1, anticorps Lrpap1, anticorps lrpap1.L
Sujet
39 kDa receptor-associated protein,A2MRAP,A2RAP,Alpha 2 macroglobulin receptor associated protein,Alpha 2 MRAP,Alpha-2-macroglobulin receptor-associated protein,Alpha-2-MRAP,AMRP,HBP44,Lipoprotein receptor associated protein,Low density lipoprotein receptor related protein associated protein 1,Low density lipoprotein receptor-related protein-associated protein 1,Low density lipoprotein related protein associated protein 1 alpha 2 macroglobulin receptor associated protein,Low density lipoprotein related protein associated protein 1,low density lipoprotein-related protein-associated protein 1 (alpha-2-macroglobulin receptor-associated protein 1),Lrpap1,MGC138272,MRAP,MYP23,RAP,Low density lipoprotein receptor-related protein associated protein 1also known asLRPAP1orRAPis a chaperoneproteinwhich in humans is encoded by the LRPAP1gene. LRPAP1 is involved with trafficking of certain members of the LDL receptor family including LRP1 and LRP2. It is a glycoprotein that binds to the alpha-2-macroglobulin receptor, as well as to other members of the low density lipoprotein receptor family. It acts to inhibit the binding of all know ligands for these receptors, and may prevent receptor aggregation and degradation in the endoplasmic reticulum, thereby acting as a molecular chaperone. It may be under the regulatory control of calmodulin, since it is able to bind calmodulin and be phosphorylated by calmodulin-dependent kinase II.